Blood

Hematopoiesis and leukemogenesis in mice expressing oncogenic NrasG12D from the endogenous locus.

Blood

Li Q, Haigis KM, McDaniel A, Harding-Theobald E, Kogan SC, Akagi K, Wong JC, Braun BS, Wolff L, Jacks T, Shannon K

Mutant BCL2 Co-Operates with CBFß/PEBP2ß-MYH11 to Promote Expansion of Leukemia Initiating Cells with a Predominantly Pro-Apoptotic Mechanism Via Recruitment of Ras-GTP In a Mouse Model of Progressive Acute Myeloid Leukemia.

Blood

Nader Omidvar, Carole Le Pogam, Stephanie Beurlet, Maria-Elena Noguera, Ann Janin, Scott C. Kogan, Irving L. Weissman, Marika Pla, Christine Chomienne, Rose Ann Padua

ABT-737 Targets Leukemic Stem Cells In Mouse Models of Mutant NRASD12/hBCL-2- Mediated Acute Myeloid Leukemia Progression with Increased Survival.

Blood

Rose Ann Padua, Stephanie Beurlet, Patricia Krief, Nader Omidvar, Carole Le Pogam, Didier Auboeuf, Pierre de la Grange, Annie Soulie, Anne Janin, Maria-Elena Noguera, Pascal Merlet, Laure Sarda-Mantel, Pierre Fenaux, Marina Konopleva, Michael Andreeff, Andrea Tu, Phoebe Yang, Alice C. Fan, Scott C. Kogan, Irving L. Weissman, Dean W. Felsher, Marika Pla, Robert West, Christine Chomienne

CD57 defines a functionally distinct population of mature NK cells in the human CD56dimCD16+ NK-cell subset.

Blood

Lopez-Vergès S, Milush JM, Pandey S, York VA, Arakawa-Hoyt J, Pircher H, Norris PJ, Nixon DF, Lanier LL

Use of chromosome engineering to model a segmental deletion of chromosome band 7q22 found in myeloid malignancies.

Blood

Wong JC, Zhang Y, Lieuw KH, Tran MT, Forgo E, Weinfurtner K, Alzamora P, Kogan SC, Akagi K, Wolff L, Le Beau MM, Killeen N, Shannon K

An Insertional Mutagenesis Screen for Genes That Cooperate with Mll-AF9 in Leukemogenesis.

Blood

Rachel Joy Bergerson, Lara S Collier, Sanne Lugthart, Raha Allaei, Molly J Nixon, Kevin A.T. Silverstein, Aaron Sarver, Danhua Flora Fan, Anne-Francoise J Lamblin, Linda Wolff, John H. Kersey, M. Gerard O'Sullivan, Ruud Delwel, Scott C. Kogan, David J Adams, David Largaespada

A linked donor-recipient study to evaluate parvovirus B19 transmission by blood component transfusion.

Blood

Kleinman SH, Glynn SA, Lee TH, Tobler LH, Schlumpf KS, Todd DS, Qiao H, Yu MY, Busch MP

Human T-cell leukemia virus type 2 produces a spliced antisense transcript encoding a protein that lacks a classic bZIP domain but still inhibits Tax2-mediated transcription.

Blood

Halin M, Douceron E, Clerc I, Journo C, Ko NL, Landry S, Murphy EL, Gessain A, Lemasson I, Mesnard JM, Barbeau B, Mahieux R

Efficient construction of producer cell lines for a SIN lentiviral vector for SCID-X1 gene therapy by concatemeric array transfection.

Blood

Throm RE, Ouma AA, Zhou S, Chandrasekaran A, Lockey T, Greene M, De Ravin SS, Moayeri M, Malech HL, Sorrentino BP, Gray JT

Myc Drives Chromosomal Gain in Acute Myeloid Leukemia.

Blood

Letetia Jones, Sabina Sevcikova, Vernon Phan, Sachi Jain, Angell Shieh, Joshua Dubansky, Min Li, Mei Lin Maunakea, George Zhu, Thelma R Tennant, Scott Lowe, Michelle M. Le, Scott C. Kogan

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