Blood

Genetic regulation of carnitine metabolism controls lipid damage repair and aging RBC hemolysis in vivo and in vitro.

Blood

Nemkov T, Key A, Stephenson D, Earley EJ, Keele GR, Hay AM, Amireault P, Casimir M, Dussiot M, Dzieciatkowska M, Reisz JA, Deng X, Stone M, Kleinman SH, Spitalnik SL, Hansen KC, Norris PJ, Churchill GA, Busch MP, Roubinian NH, Page GP, Zimring JC, Arduini A, D'Alessandro A

Genetic Regulation of Carnitine Metabolism Controls Lipid Damage Repair Mechanisms and Hemolytic Propensity of Human Red Blood Cells during Aging In Vivo and in Vitro.

Blood

Angelo D'Alessandro, Alicia Key, Pascal Amireault, Sandy Peltier, Eric Earley, Grier P Page, Travis Nemkov, Daniel Stephenson, Xutao Deng, Sonia Georgeault, Philippe Roingeard, Mars Stone, Steven Kleinman, Philip J Norris, Michael Paul Busch, Arduino Arduini

Genetic Polymorphisms in the Ferrireductase STEAP3 Regulate a Ferroptosis-like Process of Lipid Peroxidation-Induced Hemolysis in Murine and Human Red Blood Cells.

Blood

Angelo D'Alessandro, Gregory R Keele, Ariel M Hay, Travis Nemkov, Daniel Stephenson, Xutao Deng, Mars Stone, Steven Kleinman, Steven Spitalnik, Philip J Norris, Michael Paul Busch, Gary A Churchill, James C Zimring

Efficacy of the Allosteric MEK Inhibitor Trametinib in Relapsed and Refractory Juvenile Myelomonocytic Leukemia: A Report from the Children's Oncology Group.

Blood

Elliot Stieglitz, Alex Lee, Steven P. Angus, Christopher Davis, Donald Barkauskas, David Hall, Scott C. Kogan, Julia Meyer, Steven D. Rhodes, Xiaoling Xuei, Kevin Shannon, Mignon L. Loh, Elizabeth Fox, Brenda J. Weigel

Regulation of kynurenine metabolism by blood donor genetics and biology impacts red cell hemolysis in vitro and in vivo.

Blood

Nemkov T, Stephenson D, Erickson C, Dzieciatkowska M, Key A, Moore A, Earley EJ, Page GP, Lacroix IS, Stone M, Deng X, Raife TJ, Kleinman SH, Zimring JC, Roubinian NH, Hansen KC, Busch MP, Norris PJ, D'Alessandro A

The Baf Subunit Dpf2 Regulates Resolution of Inflammation By Controlling Macrophage Differentiation Transcription Factor Networks.

Blood

Gloria Mas Martin, Na Man, Daniel Karl, Concepcion Martinez, Stephanie Duffort, Hidehiro Itonaga, Adnan K Mookhtiar, Daniel Bilbao, Kranthi Kunkalla, Alfredo M Valencia, Clayton Collings, Cigall Kadoch, Francisco Vega, Scott C. Kogan, Stephen Nimer

HIV incidence in US first-time blood donors and transfusion risk with a 12-month deferral for men who have sex with men.

Blood

Grebe E, Busch MP, Notari EP, Bruhn R, Quiner C, Hindes D, Stone M, Bakkour S, Yang H, Williamson P, Kessler D, Reik R, Stramer SL, Glynn SA, Anderson SA, Williams AE, Custer B

HIV antiretroviral therapy and prevention use in US blood donors: a new blood safety concern.

Blood

Custer B, Quiner C, Haaland R, Martin A, Stone M, Reik R, Steele WR, Kessler D, Williamson PC, Anderson SA, Williams AE, Raymond HF, McFarland W, Robinson WT, Glick S, Sey K, Melton CD, Glynn SA, Stramer SL, Busch MP

Genetic disruption of N-RasG12D palmitoylation perturbs hematopoiesis and prevents myeloid transformation in mice.

Blood

Zambetti NA, Firestone AJ, Remsberg JR, Huang BJ, Wong JC, Long AM, Predovic M, Suciu RM, Inguva A, Kogan SC, Haigis KM, Cravatt BF, Shannon K

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