Philip Norris, MD

Adjunct Professor
Laboratory Medicine
[email protected]
+1 415 923-5769

Research Interests:

Understanding the role CD4+T helper cells play in the body's immune defense against viral infections, such as HIV.

Understanding acute immune response to West Nile virus and other flavivirus infection.

Defining the types and mechanisms of immune reactions associated with blood transfusion.

Publications: 

Genetic regulation of carnitine metabolism controls lipid damage repair and aging RBC hemolysis in vivo and in vitro.

Blood

Nemkov T, Key A, Stephenson D, Earley EJ, Keele GR, Hay AM, Amireault P, Casimir M, Dussiot M, Dzieciatkowska M, Reisz JA, Deng X, Stone M, Kleinman SH, Spitalnik SL, Hansen KC, Norris PJ, Churchill GA, Busch MP, Roubinian NH, Page GP, Zimring JC, Arduini A, D'Alessandro A

Patient and immunological factors associated with delayed clearance of mucosal SARS-CoV-2 RNA and symptom persistence.

The Journal of infectious diseases

Stone M, Spencer BR, Warden DE, Fink RV, Saa P, Leddy J, Mulach-Vannoy J, Townsend R, Krysztof D, Hughes AN, Di Germanio C, Kessler DA, Kleinman S, Busch MP, Norris PJ

Regulation of kynurenine metabolism by blood donor genetics and biology impacts red cell hemolysis in vitro and in vivo.

Blood

Nemkov T, Stephenson D, Erickson C, Dzieciatkowska M, Key A, Moore A, Earley EJ, Page GP, Lacroix IS, Stone M, Deng X, Raife TJ, Kleinman SH, Zimring JC, Roubinian NH, Hansen KC, Busch MP, Norris PJ, D'Alessandro A

Biological and Genetic Determinants of Glycolysis: Phosphofructokinase Isoforms Boost Energy Status of Stored Red Blood Cells and Transfusion Outcomes.

bioRxiv : the preprint server for biology

Nemkov T, Stephenson D, Earley EJ, Keele GR, Hay A, Key A, Haiman Z, Erickson C, Dzieciatkowska M, Reisz JA, Moore A, Stone M, Deng X, Kleinman S, Spitalnik SL, Hod EA, Hudson KE, Hansen KC, Palsson BO, Churchill GA, Roubinian N, Norris PJ, Busch MP, Zimring JC, Page GP, D'Alessandro A

Metabolic syndrome and surgical complications: a systematic review and meta-analysis of 13 million individuals.

International journal of surgery (London, England)

Norris P, Gow J, Arthur T, Conway A, Fleming FJ, Ralph N

Genetic polymorphisms and expression of Rhesus blood group RHCE are associated with 2,3-bisphosphoglycerate in humans at high altitude.

Proceedings of the National Academy of Sciences of the United States of America

D'Alessandro A, Earley EJ, Nemkov T, Stephenson D, Dzieciatkowska M, Hansen KC, Minetti G, Champigneulle B, Stauffer E, Pichon A, Furian M, Verges S, Kleinman S, Norris PJ, Busch MP, Page GP, Kaestner L

Clinical outcomes in hospitalized plasma and platelet transfusion recipients prior to and following widespread blood donor SARS-CoV-2 infection and vaccination.

Transfusion

Roubinian NH, Greene J, Liu VX, Lee C, Mark DG, Vinson DR, Spencer BR, Bruhn R, Bravo M, Stone M, Custer B, Kleinman S, Busch MP, Norris PJ, NHLBI Recipient Epidemiology and Donor Evaluation Study-IV-P (REDS-IV)

Local manufacturing processes contribute to variability in human mesenchymal stromal cell expansion while growth media supplements contribute to variability in gene expression and cell function: a Biomedical Excellence for Safer Transfusion (BEST) collabo

Cytotherapy

Shaz BH, Schäfer R, Fontaine MJ, Norris PJ, McKenna DH, Jin P, Reems JA, Stroncek D, Tanashi M, Marks D, Geng H, Pati S, for Biomedical Excellence for Safer Transfusion (BEST)

Genetic Polymorphisms in the Ferrireductase STEAP3 Regulate a Ferroptosis-like Process of Lipid Peroxidation-Induced Hemolysis in Murine and Human Red Blood Cells.

Blood

Angelo D'Alessandro, Gregory R Keele, Ariel M Hay, Travis Nemkov, Daniel Stephenson, Xutao Deng, Mars Stone, Steven Kleinman, Steven Spitalnik, Philip J Norris, Michael Paul Busch, Gary A Churchill, James C Zimring

Genetic Regulation of Carnitine Metabolism Controls Lipid Damage Repair Mechanisms and Hemolytic Propensity of Human Red Blood Cells during Aging In Vivo and in Vitro.

Blood

Angelo D'Alessandro, Alicia Key, Pascal Amireault, Sandy Peltier, Eric Earley, Grier P Page, Travis Nemkov, Daniel Stephenson, Xutao Deng, Sonia Georgeault, Philippe Roingeard, Mars Stone, Steven Kleinman, Philip J Norris, Michael Paul Busch, Arduino Arduini

OA2-AM23-MN-13 | Metabolite Levels from End of Storage Red Blood Cells are Reproducible Within the Same Donor Across Multiple Donations.

Transfusion

T. Nemkov, A. Key, D. Stephenson, C. Erickson, M. Stone, X. Deng, S. Kleinman, M. Busch, P. Norris, A. D'Alessandro

OA2-AM23-MN-23 | Metabolomics Analysis of Over 13,000 Donors From the REDS RBC Omics Study Identifies Markers of Hemolysis and In Vivo Hemoglobin Increments.

Transfusion

T. Nemkov, D. Stephenson, N. Roubinian, C. Erickson, M. Stone, X. Deng, S. Kleinman, M. Busch, P. Norris, A. D'Alessandro

OA3-AM23-MN-23 | Reduced Frequency of SARS-CoV-2 Symptom and RNAemia Development in Pre-Symptomatic Blood Donors with Pre-Existing Immunity.

Transfusion

P. Saa, R. Fink, C. Di Germanio, D. Krysztof, T. Nester, D. Kessler, R. Townsend, H. Kamel, M. Stone, P. Norris

OA4-AM23-MN-23 | RNA Persistence, Antibody Dynamics and Symptom Outcomes in a Longitudinal Cohort of Persons Infected with SARS-CoV-2.

Transfusion

M. Stone, R. Fink, P. Saa, A. Hughes, C. Di Germanio, B. Spencer, D. Warden, D. Kessler, S. Kleinman, P. Norris

P-CB-1 | What's in a Blood Bag? Exposome 2.0.

Transfusion

T. Nemkov, D. Stephenson, M. Stone, S. Kleinman, M. Busch, P. Norris, A. D’Alessandro

Prevalence of SARS-CoV-2 Viremia in Presymptomatic Blood Donors in the Delta and Omicron Variant Eras.

Open forum infectious diseases

Saá P, Fink RV, Dawar H, Di Germanio C, Montalvo L, Wright DJ, Krysztof DE, Kleinman SH, Nester T, Kessler DA, Townsend RL, Spencer BR, Kamel H, Vannoy J, Busch MP, Stramer SL, Stone M, Norris PJ, NHLBI Recipient Epidemiology and Donor Evaluation Study-IV-Pediatric (REDS-IV-P)

Plasma Derived Extracellular Vesicles Modulate Monocyte IL-18, IFN-a and IL-10 responses in Adults with HIV-related Cognitive Impairment.

The Journal of Immunology

Stephen T Yeung, Erika G Marques de Menezes, Courtney Friday, Jocelyn S Liu, Scott A. Bowler, Mohamed Abdel-Mohsen, Cecilia Shikuma, Philip J Norris, Lishomwa C Ndhlovu

S1P has a negative effect on RBC storage quality.

Blood advances

Hay AM, Nemkov T, Gamboni F, Dzieciatkowska M, Key A, Galbraith M, Bartsch K, Sun K, Xia Y, Stone M, Busch MP, Norris PJ, Zimring JC, D'Alessandro A

COVID-19 convalescent plasma boosts early antibody titer and does not influence the adaptive immune response.

JCI insight

McDyer JF, Azimpouran M, Durkalski-Mauldin VL, Clevenger RG, Yeatts SD, Deng X, Barsan W, Silbergleit R, El Kassar N, Popescu I, Dimitrov D, Li W, Lyons EJ, Lieber SC, Stone M, Korley FK, Callaway CW, Dumont LJ, Norris PJ

Correction to: Plasma extracellular vesicles and cell-free mitochondrial DNA are associated with cognitive dysfunction in treated older adults with HIV.

Journal of neurovirology

Johnston CD, de Menezes EGM, Bowler S, Siegler EL, Friday C, Norris PJ, Rice MC, Choi ME, Glesby MJ, Ndhlovu LC

Plasma extracellular vesicles and cell-free mitochondrial DNA are associated with cognitive dysfunction in treated older adults with HIV.

Journal of neurovirology

Johnston CD, de Menezes EGM, Bowler S, Siegler EL, Friday C, Norris PJ, Rice MC, Choi ME, Glesby MJ, Ndhlovu LC

A Stable Dried Tube Specimen for Quality Assurance and Training Programs for HIV Rapid Test for Recent Infection.

Microbiology spectrum

Di Germanio C, Yufenyuy EL, Hampton DC, Thorbrogger C, Parekh BS, Norris PJ

Circulating brain-derived extracellular vesicles expressing neuroinflammatory markers are associated with HIV-related neurocognitive impairment.

Frontiers in immunology

de Menezes EGM, Liu JS, Bowler SA, Giron LB, D'Antoni ML, Shikuma CM, Abdel-Mohsen M, Ndhlovu LC, Norris PJ

Frequent detection but lack of infectivity of SARS-CoV-2 RNA in pre-symptomatic, infected blood donor plasma.

The Journal of clinical investigation

Saá P, Fink RV, Bakkour S, Jin J, Simmons G, Muench MO, Dawar H, Di Germanio C, Hui AJ, Wright DJ, Krysztof DE, Kleinman SH, Cheung A, Nester T, Kessler DA, Townsend RL, Spencer BR, Kamel H, Vannoy JM, Dave H, Busch MP, Stramer SL, Stone M, Jackman RP, Norris PJ

A cytotoxic-skewed immune set point predicts low neutralizing antibody levels after Zika virus infection.

Cell reports

McCarthy EE, Odorizzi PM, Lutz E, Smullin CP, Tenvooren I, Stone M, Simmons G, Hunt PW, Feeney ME, Norris PJ, Busch MP, Spitzer MH, Rutishauser RL

The Recipient Epidemiology and Donor Evaluation Study-IV-Pediatric (REDS-IV-P): A research program striving to improve blood donor safety and optimize transfusion outcomes across the lifespan.

Transfusion

Josephson CD, Glynn S, Mathew S, Birch R, Bakkour S, Baumann Kreuziger L, Busch MP, Chapman K, Dinardo C, Hendrickson J, Hod EA, Kelly S, Luban N, Mast A, Norris P, Custer B, Sabino E, Sachais B, Spencer BR, Stone M, Kleinman S, National Heart, Lung, and Blood Institute (NHLBI) Recipient Epidemiology and Donor Evaluation Study-

Plasma CD16+ Extracellular Vesicles Associate with Carotid Artery Intima-Media Thickness in HIV+ Adults on Combination Antiretroviral Therapy.

mBio

Marques de Menezes EG, Deng X, Liu J, Bowler SA, Shikuma CM, Stone M, Hunt PW, Ndhlovu LC, Norris PJ

Comparative Analysis of Extracellular Vesicles in Patients with Severe and Mild Myalgic Encephalomyelitis/Chronic Fatigue Syndrome.

Frontiers in immunology

Bonilla H, Hampton D, Marques de Menezes EG, Deng X, Montoya JG, Anderson J, Norris PJ

Mesenchymal Stem Cell Extracellular Vesicles Mitigate Vascular Permeability and Injury in the Small Intestine and Lung in a Mouse Model of Hemorrhagic Shock and Trauma.

The journal of trauma and acute care surgery

Barry M, Trivedi A, Pathipati P, Miyazawa BY, Vivona LR, Togarrati PP, Khakoo M, Tanner H, Norris P, Pati S

Elevated Cerebrospinal Fluid Anti-CD4 Autoantibody Levels in HIV Associate with Neuroinflammation.

Microbiology spectrum

Cheng D, Luo Z, Fu X, Stephenson S, Di Germanio C, Norris PJ, Fuchs D, Ndhlovu LC, Li QZ, Zetterberg H, Gisslen M, Price RW, Peng S, Jiang W

Type I interferon autoantibodies are associated with systemic immune alterations in patients with COVID-19.

Science translational medicine

van der Wijst MGP, Vazquez SE, Hartoularos GC, Bastard P, Grant T, Bueno R, Lee DS, Greenland JR, Sun Y, Perez R, Ogorodnikov A, Ward A, Mann SA, Lynch KL, Yun C, Havlir DV, Chamie G, Marquez C, Greenhouse B, Lionakis MS, Norris PJ, Dumont LJ, Kelly K, Zhang P, Zhang Q, Gervais A, Le Voyer T, Whatley A, Si Y, Byrne A, Combes AJ, Rao AA, Song YS, Fragiadakis GK, Kangelaris K, Calfee CS, Erle DJ, Hendrickson C, Krummel MF, Woodruff PG, Langelier CR, Casanova JL, Derisi JL, Anderson MS, Ye CJ, UCSF COMET consortium

SARS-CoV-2 antibody magnitude and detectability are driven by disease severity, timing, and assay.

Science advances

Peluso MJ, Takahashi S, Hakim J, Kelly JD, Torres L, Iyer NS, Turcios K, Janson O, Munter SE, Thanh C, Donatelli J, Nixon CC, Hoh R, Tai V, Fehrman EA, Hernandez Y, Spinelli MA, Gandhi M, Palafox MA, Vallari A, Rodgers MA, Prostko J, Hackett J, Trinh L, Wrin T, Petropoulos CJ, Chiu CY, Norris PJ, DiGermanio C, Stone M, Busch MP, Elledge SK, Zhou XX, Wells JA, Shu A, Kurtz TW, Pak JE, Wu W, Burbelo PD, Cohen JI, Rutishauser RL, Martin JN, Deeks SG, Henrich TJ, Rodriguez-Barraquer I, Greenhouse B

Characteristics of High-Titer Convalescent Plasma and Antibody Dynamics After Administration in Patients With Severe Coronavirus Disease 2019.

Open forum infectious diseases

Bainbridge ED, Hsue PY, Esensten JH, Lynch KL, Hendrickson CM, Doernberg SB, Fung M, Chin-Hong P, Di Germanio C, Norris PJ, Simmons G, Glidden DV, Luetkemeyer AF

A bioinspired and chemically defined alternative to dimethyl sulfoxide for the cryopreservation of human hematopoietic stem cells.

Bone marrow transplantation

Gilfanova R, Callegari A, Childs A, Yang G, Luarca M, Gutierrez AG, Medina KI, Mai J, Hui A, Kline M, Wei X, Norris PJ, Muench MO

Cerebrospinal fluid and plasma lipopolysaccharide (LPS) levels in HIV-1 infection and associations with inflammation, blood-brain barrier permeability and neuronal injury.

The Journal of infectious diseases

Jiang W, Luo Z, Stephenson S, Li H, Di Germanio C, Norris PJ, Fuchs D, Zetterberg H, Gisslen M, Price RW

Neutralizing Autoantibodies to Type I Interferons in COVID-19 Convalescent Donor Plasma.

Journal of clinical immunology

Vazquez SE, Bastard P, Kelly K, Gervais A, Norris PJ, Dumont LJ, Casanova JL, Anderson MS, DeRisi JL

Compartmentalization of cerebrospinal fluid inflammation across the spectrum of untreated HIV-1 infection, central nervous system injury and viral suppression.

PloS one

Gisslen M, Keating SM, Spudich S, Arechiga V, Stephenson S, Zetterberg H, Di Germanio C, Blennow K, Fuchs D, Hagberg L, Norris PJ, Peterson J, Shacklett BL, Yiannoutsos CT, Price RW

Comparison of multiplex cytokine assays in a pediatric cohort with epilepsy.

Heliyon

Numis AL, Fox CH, Lowenstein DJ, Norris PJ, Di Germanio C

Longitudinal single-cell epitope and RNA-sequencing reveals the immunological impact of type 1 interferon autoantibodies in critical COVID-19.

bioRxiv : the preprint server for biology

van der Wijst MGP, Vazquez SE, Hartoularos GC, Bastard P, Grant T, Bueno R, Lee DS, Greenland JR, Sun Y, Perez R, Ogorodnikov A, Ward A, Mann SA, Lynch KL, Yun C, Havlir DV, Chamie G, Marquez C, Greenhouse B, Lionakis MS, Norris PJ, Dumont LJ, Kelly K, Zhang P, Zhang Q, Gervais A, Voyer TL, Whatley A, Si Y, Byrne A, Combes AJ, Rao AA, Song YS, UCSF COMET consortium , Fragiadakis GK, Kangelaris K, Calfee CS, Erle DJ, Hendrickson C, Krummel MF, Woodruff PG, Langelier CR, Casanova JL, Derisi JL, Anderson MS, Ye CJ

SARS-CoV-2 antibody magnitude and detectability are driven by disease severity, timing, and assay.

medRxiv : the preprint server for health sciences

Peluso MJ, Takahashi S, Hakim J, Kelly JD, Torres L, Iyer NS, Turcios K, Janson O, Munter SE, Thanh C, Nixon CC, Hoh R, Tai V, Fehrman EA, Hernandez Y, Spinelli MA, Gandhi M, Palafox MA, Vallari A, Rodgers MA, Prostko J, Hackett J, Trinh L, Wrin T, Petroplolous CJ, Chiu CY, Norris PJ, DiGermanio C, Stone M, Busch MP, Elledge SK, Zhou XX, Wells JA, Shu A, Kurtz TW, Pak JE, Wu W, Burbelo PD, Cohen JI, Rutishauser RL, Martin JN, Deeks SG, Henrich TJ, Rodriguez-Barraquer I, Greenhouse B

Bedside Allogeneic Erythrocyte Washing with a Cell Saver to Remove Cytokines, Chemokines, and Cell-derived Microvesicles.

Anesthesiology

Welsby IJ, Norris PJ, Mauermann WJ, Podgoreanu MV, Conn CM, Meade L, Cannon T, Keating SM, Silliman CC, Kehler M, Schulte PJ, Kor DJ

Analysis of SARS-CoV-2 antibodies in COVID-19 convalescent blood using a coronavirus antigen microarray.

Nature communications

de Assis RR, Jain A, Nakajima R, Jasinskas A, Felgner J, Obiero JM, Norris PJ, Stone M, Simmons G, Bagri A, Irsch J, Schreiber M, Buser A, Holbro A, Battegay M, Hosimer P, Noesen C, Adenaiye O, Tai S, Hong F, Milton DK, Davies DH, Contestable P, Corash LM, Busch MP, Felgner PL, Khan S

ReScan, a Multiplex Diagnostic Pipeline, Pans Human Sera for SARS-CoV-2 Antigens.

Cell reports. Medicine

Zamecnik CR, Rajan JV, Yamauchi KA, Mann SA, Loudermilk RP, Sowa GM, Zorn KC, Alvarenga BD, Gaebler C, Caskey M, Stone M, Norris PJ, Gu W, Chiu CY, Ng D, Byrnes JR, Zhou XX, Wells JA, Robbiani DF, Nussenzweig MC, DeRisi JL, Wilson MR

Seminal Plasma-Derived Extracellular-Vesicle Fractions from HIV-Infected Men Exhibit Unique MicroRNA Signatures and Induce a Proinflammatory Response in Cells Isolated from the Female Reproductive Tract.

Journal of virology

Marques de Menezes EG, Jang K, George AF, Nyegaard M, Neidleman J, Inglis HC, Danesh A, Deng X, Afshari A, Kim YH, Billaud JN, Marson K, Pilcher CD, Pillai SK, Norris PJ, Roan NR

Analysis of SARS-CoV-2 Antibodies in COVID-19 Convalescent Plasma using a Coronavirus Antigen Microarray.

bioRxiv : the preprint server for biology

de Assis RR, Jain A, Nakajima R, Jasinskas A, Felgner J, Obiero JM, Adenaiye O, Tai S, Hong F, Norris P, Stone M, Simmons G, Bagri A, Schreiber M, Buser A, Holbro A, Battegay M, Milton DK, Davies H, Corash LM, Busch MP, Felgner PL, Khan S

Early Inflammatory Signatures Predict Subsequent Cognition in Long-Term Virally Suppressed Women With HIV.

Frontiers in integrative neuroscience

Rubin LH, Xu Y, Norris PJ, Wang X, Dastgheyb R, Fitzgerald KC, Keating SM, Kaplan RC, Maki PM, Anastos K, Springer G, Benning L, Kassaye S, Gustafson DR, Valcour VG, Williams DW

Influence of sickle cell disease on susceptibility to HIV infection.

PloS one

Kelly S, Jacobs ES, Stone M, Keating SM, Lee TH, Chafets D, Heitman J, Dimapasoc M, Operskalski E, Hagar W, Vichinsky E, Busch MP, Norris PJ, Custer B

Seminal plasma promotes decidualization of endometrial stromal fibroblasts in vitro from women with and without inflammatory disorders in a manner dependent on interleukin-11 signaling.

Human reproduction (Oxford, England)

George AF, Jang KS, Nyegaard M, Neidleman J, Spitzer TL, Xie G, Chen JC, Herzig E, Laustsen A, Marques de Menezes EG, Houshdaran S, Pilcher CD, Norris PJ, Jakobsen MR, Greene WC, Giudice LC, Roan NR

Red-blood-cell manufacturing methods and storage solutions differentially induce pulmonary cell activation.

Vox sanguinis

Wirtz MR, Almizraq RJ, Weber NC, Norris PJ, Pandey S, Spinella PC, Muszynski JA, P Acker J, Juffermans NP

Serum extracellular vesicles expressing bone activity markers associate with bone loss after HIV antiretroviral therapy.

AIDS (London, England)

Marques de Menezes EG, Ramallho J, Bucovsky M, Shane E, Yin MT, Norris PJ

Cerebrospinal fluid soluble CD30 elevation despite suppressive antiretroviral therapy in individuals living with HIV-1.

Journal of virus eradication

Peluso MJ, Thanh C, Prator CA, Hogan LE, Arechiga VM, Stephenson S, Norris PJ, Di Germanio C, Fuchs D, Zetterberg H, Deeks SG, Gisslén M, Price RW, Henrich TJ

Prostate cancer survivorship priorities for men and their partners: Delphi consensus from a nurse specialist cohort.

Journal of clinical nursing

Ralph N, Green A, Sara S, McDonald S, Norris P, Terry V, Dunn JC, Chambers SK

Lack of persistent microchimerism in contemporary transfused trauma patients.

Transfusion

Jackman RP, Utter GH, Lee TH, Montalvo L, Wen L, Chafets D, Rivers RM, Kopko PM, Norris PJ, Busch MP

Zika Virus-Immune Plasmas from Symptomatic and Asymptomatic Individuals Enhance Zika Pathogenesis in Adult and Pregnant Mice.

mBio

Shim BS, Kwon YC, Ricciardi MJ, Stone M, Otsuka Y, Berri F, Kwal JM, Magnani DM, Jackson CB, Richard AS, Norris P, Busch M, Curry CL, Farzan M, Watkins D, Choe H

Biospecimen Science of Blood for Peripheral Blood Mononuclear Cell (PBMC) Functional Applications.

Current Pathobiology Reports

Fay Betsou, Amelie Gaignaux, Wim Ammerlaan, Philip J. Norris, Mars Stone

Potential of Membranes Surrounding the Fetus as Immunoprotective Cell-Carriers for Allogeneic Transplantations.

Transplantation direct

Togarrati PP, Dinglasan N, Yee E, Heitman JW, Jackman RP, Geisberg M, Norris PJ, Bárcena A, Muench MO

Bone marrow donor selection and characterization of MSCs is critical for pre-clinical and clinical cell dose production.

Journal of translational medicine

Trivedi A, Miyazawa B, Gibb S, Valanoski K, Vivona L, Lin M, Potter D, Stone M, Norris PJ, Murphy J, Smith S, Schreiber M, Pati S

Influence of blood storage age on immune and coagulation parameters in critically ill transfused patients.

Transfusion

Norris PJ, Schechtman K, Inglis HC, Adelman A, Heitman JW, Vilardi R, Shah A, Roubinian NH, Danesh A, Guiltinan AM, Keating SM, Lacroix J, Cohen MJ, Spinella PC

Therapeutic impact of red blood cell transfusion on anemic outpatients: the RETRO study.

Transfusion

St Lezin E, Karafin MS, Bruhn R, Chowdhury D, Qu L, Bialkowski W, Merenda S, D'Andrea P, McCalla AL, Anderson L, Keating SM, Stone M, Snyder EL, Brambilla D, Murphy EL, Norris PJ, Hilton JF, Spencer BR, Kleinman S, Carson JL

Effects of blood storage age on immune, coagulation, and nitric oxide parameters in transfused patients undergoing cardiac surgery.

Transfusion

Spinella PC, Sniecinski RM, Trachtenberg F, Inglis HC, Ranganathan G, Heitman JW, Szlam F, Danesh A, Stone M, Keating SM, Levy JH, Assmann SF, Steiner ME, Doctor A, Norris PJ

Abstract 52: Inflammatory Biomarkers Correlate With Etiology in Childhood Arterial Ischemic Stroke.

Stroke

Heather J Fullerton, Nancy K Hills, Max Wintermark, Philip Norris, John Heitman, Sheila Keating, Rachel Owen

The role of pathogen-reduced platelet transfusions on HLA alloimmunization in hemato-oncological patients.

Transfusion

Saris A, Kerkhoffs JL, Norris PJ, van Ham SM, Ten Brinke A, Brand A, van der Meer PF, Zwaginga JJ

Prevalence and risk factors for RBC alloantibodies in blood donors in the Recipient Epidemiology and Donor Evaluation Study-III (REDS-III).

Transfusion

Karafin MS, Tan S, Tormey CA, Spencer BR, Hauser RG, Norris PJ, Roubinian NH, Wu Y, Triulzi DJ, Kleinman S, Gottschall JL, Hendrickson JE

Blood manufacturing methods affect red blood cell product characteristics and immunomodulatory activity.

Blood advances

Almizraq RJ, Norris PJ, Inglis H, Menocha S, Wirtz MR, Juffermans N, Pandey S, Spinella PC, Acker JP, Muszynski JA

Increased alloreactive and autoreactive antihuman leucocyte antigen antibodies associated with systemic lupus erythematosus and rheumatoid arthritis.

Lupus science & medicine

Jackman RP, Cruz GI, Nititham J, Triulzi DJ, Barcellos LF, Criswell LA, Norris PJ, Busch MP

Evolution of Validated Biomarkers and Intraoperative Parameters in the Development of Postoperative ARDS.

Respiratory care

Yadav H, Bartley A, Keating S, Meade LA, Norris PJ, Carter RE, Gajic O, Kor DJ

Hemostatic efficacy of pathogen-inactivated vs untreated platelets: a randomized controlled trial.

Blood

van der Meer PF, Ypma PF, van Geloven N, van Hilten JA, van Wordragen-Vlaswinkel RJ, Eissen O, Zwaginga JJ, Trus M, Beckers EAM, Te Boekhorst P, Tinmouth A, Lin Y, Hsia C, Lee D, Norris PJ, Goodrich RP, Brand A, Hervig T, Heddle NM, van der Bom JG, Kerkhoffs JH

Granulocyte-Derived Extracellular Vesicles Activate Monocytes and Are Associated With Mortality in Intensive Care Unit Patients.

Frontiers in immunology

Danesh A, Inglis HC, Abdel-Mohsen M, Deng X, Adelman A, Schechtman KB, Heitman JW, Vilardi R, Shah A, Keating SM, Cohen MJ, Jacobs ES, Pillai SK, Lacroix J, Spinella PC, Norris PJ

Granulocyte-derived extracellular vesicles activate monocytes and are associated with mortality in ICU patients.

The Journal of Immunology

Philip Norris, Heather C. Inglis, Mohamed Abdel-Mohsen, Xutao Deng, Avril Adelman, Kenneth B. Schechtman, Sheila Marie Keating, Mitchell J. Cohen, Evan S. Jacobs, Satish Pillai, Jacques Lacroix, Philip C. Spinella, Ali Danesh

‘Plasma monocyte-derived extracellular vesicles are associated with neurocognitive impairment in HIV infected individuals.’.

The Journal of Immunology

Erika Grasiela Marques de Menezes, Heather C. Inglis, Michelle D’Antoni, Cecilia M. Shikuma, Lishomwa C. Ndhlovu, Philip Norris

Alloreactive fetal T cells promote uterine contractility in preterm labor via IFN-? and TNF-a.

Science translational medicine

Frascoli M, Coniglio L, Witt R, Jeanty C, Fleck-Derderian S, Myers DE, Lee TH, Keating S, Busch MP, Norris PJ, Tang Q, Cruz G, Barcellos LF, Gomez-Lopez N, Romero R, MacKenzie TC

Risk factors for red blood cell alloimmunization in the Recipient Epidemiology and Donor Evaluation Study (REDS-III) database.

British journal of haematology

Karafin MS, Westlake M, Hauser RG, Tormey CA, Norris PJ, Roubinian NH, Wu Y, Triulzi DJ, Kleinman S, Hendrickson JE

In vitro basal T-cell proliferation among asymptomatic Human T cell Leukemia Virus type 1 patients co-infected with hepatitis C and/or Human Immunodeficiency Virus type 1.

The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases

Assone T, Kanashiro TM, Baldassin MPM, Paiva A, Haziot ME, Smid J, Oliveira AP, Fonseca LAM, Norris PJ, Casseb J

Ultraviolet light-based pathogen inactivation and alloimmunization after platelet transfusion: results from a randomized trial.

Transfusion

Norris PJ, Kaidarova Z, Maiorana E, Milani S, Lebedeva M, Busch MP, Custer B, Rebulla P

Mechanisms of red blood cell transfusion-related immunomodulation.

Transfusion

Remy KE, Hall MW, Cholette J, Juffermans NP, Nicol K, Doctor A, Blumberg N, Spinella PC, Norris PJ, Dahmer MK, Muszynski JA

Identification and Validation of HIV Cofactors.

Oliver Taltynov, Jan De Rijck, Zeger Debyser, Lyle R. McKinnon, Jo-Ann S. Passmore, Geneviève Boily-Larouche, Yoav Kenyan, Keith Raymond Fowke, Louis-Marie Yindom, Robert Walton, Martyn A. French, Robert W. Buckheit, Joel N. Blankson, Christina C. Chang, Megan Crane, Anthony Jaworowski, Andrew Lloyd, Martyn A. French, Sharon R. Lewin, Fabien P. Blanchet, Sheila M. Keating, Evan S. Jacobs, Philip J. Norris, Bin Su, Maryse Peressin, Christiane Moog, Joel Gallant, Jill Blumenthal, Charles Hicks, Angela Ciuffi, Frederic D. Bushman, Ester Ballana, José A. Esté, Shmona Simpson, Sabelle Jallow

Inflammatory Cytokines.

Encyclopedia of AIDS

Sheila M. Keating, Evan S. Jacobs, Philip J. Norris

Proceedings of the Food and Drug Administration's public workshop on new red blood cell product regulatory science 2016.

Transfusion

Vostal JG, Buehler PW, Gelderman MP, Alayash AI, Doctor A, Zimring JC, Glynn SA, Hess JR, Klein H, Acker JP, Spinella PC, D'Alessandro A, Palsson B, Raife TJ, Busch MP, McMahon TJ, Intaglietta M, Swartz HM, Dubick MA, Cardin S, Patel RP, Natanson C, Weisel JW, Muszynski JA, Norris PJ, Ness PM

Genomewide association study of HLA alloimmunization in previously pregnant blood donors.

Transfusion

Seielstad M, Page GP, Gaddis N, Lanteri M, Lee TH, Kakaiya R, Barcellos LF, Criswell LA, Triulzi D, Norris PJ, Busch MP

Polymorphisms in HLA-C and KIR alleles are not associated with HAM/TSP risk in HTLV-1-infected subjects.

Virus research

Assone T, Malta FM, Bakkour S, Montalvo L, Paiva AM, Smid J, de Oliveira ACP, de Toledo Gonçalves F, do Carmo Luiz O, Fonseca LAM, Norris PJ, Casseb J

Variability in C-reactive protein is associated with cognitive impairment in women living with and without HIV: a longitudinal study.

Journal of neurovirology

Rubin LH, Benning L, Keating SM, Norris PJ, Burke-Miller J, Savarese A, Kumanan KN, Awadalla S, Springer G, Anastos K, Young M, Milam J, Valcour VG, Weber KM, Maki PM

The effect of HIV infection and HCV viremia on inflammatory mediators and hepatic injury-The Women's Interagency HIV Study.

PloS one

Keating SM, Dodge JL, Norris PJ, Heitman J, Gange SJ, French AL, Glesby MJ, Edlin BR, Latham PS, Villacres MC, Greenblatt RM, Peters MG

Plasminogen Activator Inhibitor-1 Predicts Negative Alterations in Whole-Body Insulin Sensitivity in Chronic HIV Infection.

AIDS research and human retroviruses

Wirunsawanya K, Belyea L, Shikuma C, Watanabe RM, Kohorn L, Shiramizu B, Mitchell BI, Souza SA, Keating SM, Norris PJ, Ndhlovu LC, Chow D

How do i participate in T-cell immunotherapy?

Transfusion

Suhoski Davis MM, McKenna DH, Norris PJ

Cytokines Elevated in HIV Elite Controllers Reduce HIV Replication In Vitro and Modulate HIV Restriction Factor Expression.

Journal of virology

Jacobs ES, Keating SM, Abdel-Mohsen M, Gibb SL, Heitman JW, Inglis HC, Martin JN, Zhang J, Kaidarova Z, Deng X, Wu S, Anastos K, Crystal H, Villacres MC, Young M, Greenblatt RM, Landay AL, Gange SJ, Deeks SG, Golub ET, Pillai SK, Norris PJ

Reduced MHC alloimmunization and partial tolerance protection with pathogen reduction of whole blood.

Transfusion

Jackman RP, Muench MO, Inglis H, Heitman JW, Marschner S, Goodrich RP, Norris PJ

An association between ABO group and HLA antibody detection.

Transfusion

Dunbar NM, Yazer MH, Bravo MD, Kamel HT, Gorlin J, Norris PJ, Williamson PC, Vassallo RR

Magnitude and Quality of Cytokine and Chemokine Storm during Acute Infection Distinguish Nonprogressive and Progressive Simian Immunodeficiency Virus Infections of Nonhuman Primates.

Journal of virology

Keating SM, Heitman JW, Wu S, Deng X, Stacey AR, Zahn RC, de la Rosa M, Finstad SL, Lifson JD, Piatak M, Gauduin MC, Kessler BM, Ternette N, Carville A, Johnson RP, Desrosiers RC, Letvin NL, Borrow P, Norris PJ, Schmitz JE

Transfusion-related immunomodulation: review of the literature and implications for pediatric critical illness.

Transfusion

Muszynski JA, Spinella PC, Cholette JM, Acker JP, Hall MW, Juffermans NP, Kelly DP, Blumberg N, Nicol K, Liedel J, Doctor A, Remy KE, Tucci M, Lacroix J, Norris PJ

High 25-hydroxyvitamin D is associated with unexpectedly high plasma inflammatory markers in HIV patients on antiretroviral therapy.

Medicine

Gangcuangco LM, Kohorn LB, Chow DC, Keating SM, Norris PJ, Nagamine LS, Ndhlovu LC, Souza SA, Kallianpur KJ, Shikuma CM

Human Galectin-9 Is a Potent Mediator of HIV Transcription and Reactivation.

PLoS pathogens

Abdel-Mohsen M, Chavez L, Tandon R, Chew GM, Deng X, Danesh A, Keating S, Lanteri M, Samuels ML, Hoh R, Sacha JB, Norris PJ, Niki T, Shikuma CM, Hirashima M, Deeks SG, Ndhlovu LC, Pillai SK

Differences in the Selection Bottleneck between Modes of Sexual Transmission Influence the Genetic Composition of the HIV-1 Founder Virus.

PLoS pathogens

Tully DC, Ogilvie CB, Batorsky RE, Bean DJ, Power KA, Ghebremichael M, Bedard HE, Gladden AD, Seese AM, Amero MA, Lane K, McGrath G, Bazner SB, Tinsley J, Lennon NJ, Henn MR, Brumme ZL, Norris PJ, Rosenberg ES, Mayer KH, Jessen H, Kosakovsky Pond SL, Walker BD, Altfeld M, Carlson JM, Allen TM

Non-classical monocytes predict progression of carotid artery bifurcation intima-media thickness in HIV-infected individuals on stable antiretroviral therapy.

HIV clinical trials

Chow DC, Kagihara JM, Zhang G, Souza SA, Hodis HN, Li Y, Mitchell BI, Nakamoto BK, Kallianpur KJ, Keating SM, Norris PJ, Kohorn LB, Ndhlovu LC, Shikuma CM

Reduced alloimmunization in mice following repeated transfusion with pathogen-reduced platelets.

Transfusion

Muench MO, Heitman JW, Inglis H, Fomin ME, Marschner S, Goodrich RP, Norris PJ, Jackman RP

The effects of 22°C and 4°C storage of platelets on vascular endothelial integrity and function.

Transfusion

Baimukanova G, Miyazawa B, Potter DR, Gibb SL, Keating S, Danesh A, Beyer A, Dayter Y, Bruhn R, Muench MO, Cap AP, Norris PJ, Spinella P, Cohen M, Pati S

Manufacturing method affects mitochondrial DNA release and extracellular vesicle composition in stored red blood cells.

Vox sanguinis

Bakkour S, Acker JP, Chafets DM, Inglis HC, Norris PJ, Lee TH, Busch MP

Non-Classical Monocytes and Monocyte Chemoattractant Protein-1 (MCP-1) Correlate with Coronary Artery Calcium Progression in Chronically HIV-1 Infected Adults on Stable Antiretroviral Therapy.

PloS one

Zungsontiporn N, Tello RR, Zhang G, Mitchell BI, Budoff M, Kallianpur KJ, Nakamoto BK, Keating SM, Norris PJ, Ndhlovu LC, Souza SA, Shikuma CM, Chow DC

Systemic Cytokine Levels Do Not Predict CD4(+) T-Cell Recovery After Suppressive Combination Antiretroviral Therapy in Chronic Human Immunodeficiency Virus Infection.

Open forum infectious diseases

Norris PJ, Zhang J, Worlock A, Nair SV, Anastos K, Minkoff HL, Villacres MC, Young M, Greenblatt RM, Desai S, Landay AL, Gange SJ, Nugent CT, Golub ET, Keating SM

Neuroinvasive West Nile Infection Elicits Elevated and Atypically Polarized T Cell Responses That Promote a Pathogenic Outcome.

PLoS pathogens

James EA, Gates TJ, LaFond RE, Yamamoto S, Ni C, Mai D, Gersuk VH, O'Brien K, Nguyen QA, Zeitner B, Lanteri MC, Norris PJ, Chaussabel D, Malhotra U, Kwok WW

In vitro basal T-cell proliferation and HTLV-1 proviral load among HTLV-1 subjects co-infected with Hepatitis C and/or HIV-1.

Retrovirology

Tatiane Assone, Tatiana Mitiko, Samara PC Gomes, Arthur Paiva, Michel Haziot, Jerusa Smid, Augusto Penalva de Oliveira, Philip J Norris, Jorge Casseb

Serum amyloid P (SAP) is associated with impaired brachial artery flow-mediated dilation in chronically HIV-1 infected adults on stable antiretroviral therapy.

HIV clinical trials

Zungsontiporn N, Ndhlovu LC, Mitchell BI, Stein JH, Kallianpur KJ, Nakamoto B, Keating SM, Norris PJ, Souza SA, Shikuma CM, Chow DC

Serum amyloid P (SAP) is associated with impaired brachial artery flow-mediated dilation in chronically HIV-1 infected adults on stable antiretroviral therapy.

HIV clinical trials

Zungsontiporn N, Ndhlovu LC, Mitchell BI, Stein JH, Kallianpur KJ, Nakamoto B, Keating SM, Norris PJ, Souza SA, Shikuma CM, Chow DC

All plasma products are not created equal: Characterizing differences between plasma products.

The journal of trauma and acute care surgery

Spinella PC, Frazier E, Pidcoke HF, Dietzen DJ, Pati S, Gorkun O, Aden JK, Norris PJ, Cap AP

Soluble Tim-3 is shed from CD8+ T cells by the sheddase ADAM10, is increased in plasma during untreated HIV infection, and correlates with HIV disease progression (VIR6P.1165).

The Journal of Immunology

Kiera Clayton, Matthew Douglas-Vail, A. Rahman, Karyn Medcalf, Irene Xie, Glen Chew, Ravi Tandon, Marion Lanteri, Philip Norris, Steven Deeks, Lishomwa Ndhlovu, Mario Ostrowski

Techniques to improve detection and analysis of extracellular vesicles using flow cytometry.

Cytometry. Part A : the journal of the International Society for Analytical Cytology

Inglis HC, Danesh A, Shah A, Lacroix J, Spinella PC, Norris PJ

Techniques for the analysis of extracellular vesicles using flow cytometry.

Journal of visualized experiments : JoVE

Inglis H, Norris P, Danesh A

The effect of processing method on the in vitro characteristics of red blood cell products.

Vox sanguinis

Hansen AL, Kurach JD, Turner TR, Jenkins C, Busch MP, Norris PJ, Dugger J, Tomasulo PA, Devine DV, Acker JP

Soluble T cell immunoglobulin mucin domain 3 is shed from CD8+ T cells by the sheddase ADAM10, is increased in plasma during untreated HIV infection, and correlates with HIV disease progression.

Journal of virology

Clayton KL, Douglas-Vail MB, Nur-ur Rahman AK, Medcalf KE, Xie IY, Chew GM, Tandon R, Lanteri MC, Norris PJ, Deeks SG, Ndhlovu LC, Ostrowski MA

Recipient clinical risk factors predominate in possible transfusion-related acute lung injury.

Transfusion

Toy P, Bacchetti P, Grimes B, Gajic O, Murphy EL, Winters JL, Gropper MA, Hubmayr RD, Matthay MA, Wilson G, Koenigsberg M, Lee DC, Hirschler NV, Lowell CA, Schuller RM, Gandhi MJ, Norris PJ, Mair DC, Sanchez Rosen R, Looney MR

C1q-Binding HLA Antibodies Do Not Predict Platelet Transfusion Failure in TRAP Study Participant.

Blood

Rachael P. Jackman, Douglas Bolgiano, Mila Lebedeva, Sherrill J. Slichter, Philip J. Norris

Downregulation of Cytokines and Chemokines By GB Virus C after Transfusion-Transmission in HIV+ Blood Recipients.

Blood

Marion Lanteri, Farnaz Vahidnia, Sylvia Tan, Jack Stapleton, Philip J. Norris, John W. Heitman, Xutao Deng, Sheila Keating, Donald Brambilla, Michael Busch, Brian Custer

Albuminuria is associated with elevated acute phase reactants and proinflammatory markers in HIV-infected patients receiving suppressive combination antiretroviral therapy.

AIDS research and human retroviruses

O-charoen P, Ndhlovu LC, Gangcuangco LM, Keating SM, Norris PJ, Ng RC, Mitchell BI, Shikuma CM, Chow DC

Downregulation of Cytokines and Chemokines by GB Virus C After Transmission Via Blood Transfusion in HIV-Positive Blood Recipients.

The Journal of infectious diseases

Lanteri MC, Vahidnia F, Tan S, Stapleton JT, Norris PJ, Heitman J, Deng X, Keating SM, Brambilla D, Busch MP, Custer B

Role of microRNA modulation in the interferon-a/ribavirin suppression of HIV-1 in vivo.

PloS one

Abdel-Mohsen M, Deng X, Danesh A, Liegler T, Jacobs ES, Rauch A, Ledergerber B, Norris PJ, Günthard HF, Wong JK, Pillai SK

Prospective study on the clinical course and outcomes in transfusion-related acute lung injury*.

Critical care medicine

Looney MR, Roubinian N, Gajic O, Gropper MA, Hubmayr RD, Lowell CA, Bacchetti P, Wilson G, Koenigsberg M, Lee DC, Wu P, Grimes B, Norris PJ, Murphy EL, Gandhi MJ, Winters JL, Mair DC, Schuller RM, Hirschler NV, Rosen RS, Matthay MA, Toy P

West Nile virus nucleic acid persistence in whole blood months after clearance in plasma: implication for transfusion and transplantation safety.

Transfusion

Lanteri MC, Lee TH, Wen L, Kaidarova Z, Bravo MD, Kiely NE, Kamel HT, Tobler LH, Norris PJ, Busch MP

Galectin-9 is rapidly released during acute HIV-1 infection and remains sustained at high levels despite viral suppression even in elite controllers.

AIDS research and human retroviruses

Tandon R, Chew GM, Byron MM, Borrow P, Niki T, Hirashima M, Barbour JD, Norris PJ, Lanteri MC, Martin JN, Deeks SG, Ndhlovu LC

Increased frequency of Tim-3 expressing T cells is associated with symptomatic West Nile virus infection.

PloS one

Lanteri MC, Diamond MS, Law JP, Chew GM, Wu S, Inglis HC, Wong D, Busch MP, Norris PJ, Ndhlovu LC

HIV RNA levels in plasma and cervical-vaginal lavage fluid in elite controllers and HAART recipients.

AIDS (London, England)

Landay A, Golub ET, Desai S, Zhang J, Winkelman V, Anastos K, Durkin H, Young M, Villacres MC, Greenblatt RM, Norris PJ, Busch MP

Monocytes expand with immune dysregulation and is associated with insulin resistance in older individuals with chronic HIV.

PloS one

Shikuma CM, Chow DC, Gangcuangco LM, Zhang G, Keating SM, Norris PJ, Seto TB, Parikh N, Kallianpur KJ, Nakamoto BK, Nagamine LS, Ndhlovu LC, Barbour JD

Inflammatory Cytokines.

Encyclopedia of AIDS

Sheila M. Keating, Evan S. Jacobs, Philip J. Norris

Exosomes from red blood cell units bind to monocytes and induce proinflammatory cytokines, boosting T-cell responses in vitro.

Blood

Danesh A, Inglis HC, Jackman RP, Wu S, Deng X, Muench MO, Heitman JW, Norris PJ

Reduced CD14 expression on classical monocytes and vascular endothelial adhesion markers independently associate with carotid artery intima media thickness in chronically HIV-1 infected adults on virologically suppressive anti-retroviral therapy.

Atherosclerosis

Barbour JD, Jalbert EC, Chow DC, Gangcuangco LM, Norris PJ, Keating SM, Heitman J, Nagamine L, Seto T, Ndhlovu LC, Nakamoto BK, Hodis HN, Parikh NI, Shikuma CM

Cytokine and chemokine responses in the acute phase of hepatitis B virus replication in naive and previously vaccinated blood and plasma donors.

The Journal of infectious diseases

Keating SM, Heitman JD, Wu S, Deng X, Stramer SL, Kuhns MC, Mullen C, Norris PJ, Busch MP

IL-1? enriched monocytes mount massive IL-6 responses to common inflammatory triggers among chronically HIV-1 infected adults on stable anti-retroviral therapy at risk for cardiovascular disease.

PloS one

Jalbert E, Crawford TQ, D'Antoni ML, Keating SM, Norris PJ, Nakamoto BK, Seto T, Parikh NI, Shikuma CM, Ndhlovu LC, Barbour JD

Plasma monocyte chemoattractant protein-1 and tumor necrosis factor-a levels predict the presence of coronary artery calcium in HIV-infected individuals independent of traditional cardiovascular risk factors.

AIDS research and human retroviruses

Shikuma CM, Barbour JD, Ndhlovu LC, Keating SM, Norris PJ, Budoff M, Parikh N, Seto T, Gangcuangco LM, Ogata-Arakaki D, Chow D

143 Cytokine patterns associated with persistent inflammation or viremic control in HIV infection.

Cytokine

Sheila M. Keating, Evan Jacobs, Busola Adesina, Shiquan Wu, Elizabeth T. Golub, John W. Heitman, Marek Nowicki, Maria Villacres, Mary Young, Kathryn Anastos, Howard Crystal, Steven G. Deeks, Jeff N. Martin, Jinbing Zhang, Ruth M. Greenblatt, Alan L. Landay, Philip J. Norris, the Women’s Interagency HIV Study

Innate immune responses in acute HIV-1 infection: protective or pathogenic?.

Retrovirology

Persephone Borrow, Andrea Stacey, Angharad Fenton-May, Oliver Dibben, Elizabeth Haygreen, Tanja Emmerich, Norma Kim, Elizabeth Marshall, Kerry Lavender, Myron Cohen, Paul Goepfert, Ian Williams, Dennis Wallace, George Shaw, Beatrice Hahn, Christina Ochsenbauer, John Kappes, Philip Norris, Andrew McMichael, Barton Haynes

Leukoreduction and ultraviolet treatment reduce both the magnitude and the duration of the HLA antibody response.

Transfusion

Jackman RP, Deng X, Bolgiano D, Utter GH, Schechterly C, Lebedeva M, Operskalski E, Luban NL, Alter H, Busch MP, Slichter SJ, Norris PJ

Fetal production of growth factors and inflammatory mediators predicts pulmonary hypertension in congenital diaphragmatic hernia.

Pediatric research

Fleck S, Bautista G, Keating SM, Lee TH, Keller RL, Moon-Grady AJ, Gonzales K, Norris PJ, Busch MP, Kim CJ, Romero R, Lee H, Miniati D, MacKenzie TC

Treatment-related changes in serum lipids and inflammation: clinical relevance remains unclear. Analyses from the Women's Interagency HIV study.

AIDS (London, England)

Parrinello CM, Landay AL, Hodis HN, Gange SJ, Norris PJ, Young M, Anastos K, Tien PC, Xue X, Lazar J, Benning L, Tracy RP, Kaplan RC

Detection of microparticles in human plasma using flow cytometry: limitations and optimization techniques. (P3265).

The Journal of Immunology

Philip Norris, Ali Danesh, Dale Hirschkorn, Heather Inglis

Immune modulation and prevention of alloimmunization following transfusion with pathogen reduced platelets (P2144).

The Journal of Immunology

Rachael Jackman, Marcus Muench, John Heitman, Heather Inglis, Jacqueline Law, Susanne Marschner, Raymond Goodrich, Philip Norris

Increased frequency of Tim-3+ T cells is associated with symptomatic WNV disease clinical outcome (P6085).

The Journal of Immunology

Marion Lanteri, Michael Diamond, Jennifer Govero, Amelia Pinto, Jacqueline Law, Glen Chew, Shiquan Wu, Toshiro Niki, Heather Inglis, Mitsuomi Hirashima, Michael Busch, Philip Norris, Lishomwa Ndhlovu

Rapid Galectin-9 release occurs following HIV-1 acquisition in acute HIV-1 infection (P6165).

The Journal of Immunology

Ravi Tandon, Tsuyoshi Fujita, Glen Chew, Mary Margaret Byron, Toshiro Niki, Mitsuomi Hirashima, Jason Barbour, Mario Ostrowski, Kiera Clayton, Marion Lanteri, Naoto Ishii, Persephone Borrow, Philip Norris, Frederick Hecht, Lishomwa Ndhlovu

T lymphocyte responses to RBC-derived microparticles are APC-dependent (P1040).

The Journal of Immunology

Ali Danesh, Heather Inglis, John Heitman, Philip Norris

Immune modulation and lack of alloimmunization following transfusion with pathogen-reduced platelets in mice.

Transfusion

Jackman RP, Muench MO, Heitman JW, Inglis HC, Law JP, Marschner S, Goodrich RP, Norris PJ

CD57 expression and cytokine production by T cells in lesional and unaffected skin from patients with psoriasis.

PloS one

Batista MD, Tincati C, Milush JM, Ho EL, Ndhlovu LC, York VA, Kallas EG, Kalil J, Keating SM, Norris PJ, Chang D, Unemori P, Leslie KS, Maurer T, Liao W, Nixon DF

Low-level HLA antibodies do not predict platelet transfusion failure in TRAP study participants.

Blood

Jackman RP, Deng X, Bolgiano D, Lebedeva M, Heitman JW, Busch MP, Slichter SJ, Norris PJ

Lot-to-lot variability in HLA antibody screening using a multiplexed bead-based assay.

Transfusion

Gandhi MJ, Carrick DM, Jenkins S, De Goey S, Ploeger NA, Wilson GA, Lee JH, Winters JL, Stubbs JR, Toy P, Norris PJ

481: Maternal-fetal cellular trafficking and fetal inflammation in patients with preterm premature rupture of membranes.

American Journal of Obstetrics and Gynecology

Dana Henry, Yvonne Cheng, Payam Saadai, Sheila Keating, Tzong-Hae Lee, Philip Norris, Michael Busch, Roberto Romero, Tippi MacKenzie

IL-1ß signaling promotes CNS-intrinsic immune control of West Nile virus infection.

PLoS pathogens

Ramos HJ, Lanteri MC, Blahnik G, Negash A, Suthar MS, Brassil MM, Sodhi K, Treuting PM, Busch MP, Norris PJ, Gale M

Association of subclinical atherosclerosis with lipid levels amongst antiretroviral-treated and untreated HIV-infected women in the Women's Interagency HIV study.

Atherosclerosis

Parrinello CM, Landay AL, Hodis HN, Gange SJ, Norris PJ, Young M, Anastos K, Tien PC, Xue X, Lazar J, Benning L, Tracy RP, Kaplan RC

Lower-sensitivity and avidity modifications of the vitros anti-HIV 1+2 assay for detection of recent HIV infections and incidence estimation.

Journal of clinical microbiology

Keating SM, Hanson D, Lebedeva M, Laeyendecker O, Ali-Napo NL, Owen SM, Stramer SL, Moore RD, Norris PJ, Busch MP

Potential cardiovascular disease risk markers among HIV-infected women initiating antiretroviral treatment.

Journal of acquired immune deficiency syndromes (1999)

Kaplan RC, Landay AL, Hodis HN, Gange SJ, Norris PJ, Young M, Anastos K, Tien PC, Xue X, Lazar J, Parrinello CM, Benning L, Tracy RP

Detection of host immune responses in acute phase sera of spontaneous resolution versus persistent hepatitis C virus infection.

The Journal of general virology

Selvarajah S, Keating S, Heitman J, Lu K, Simmons G, Norris PJ, Operskalski E, Mosley JW, Busch MP

Measures to prevent transfusion-related acute lung injury (TRALI).

Vox sanguinis

Reesink HW, Lee J, Keller A, Dennington P, Pink J, Holdsworth R, Schennach H, Goldman M, Petraszko T, Sun J, Meng Y, Qian K, Rehacek V, Turek P, Krusius T, Juvonen E, Tiberghien P, Legrand D, Semana G, Muller JY, Bux J, Reil A, Lin CK, Daly H, McSweeney E, Porretti L, Greppi N, Rebulla P, Okazaki H, Sánchez-Guerrero SA, Baptista-González HA, Martínez-Murillo C, Guerra-Márquez A, Rodriguez-Moyado H, Middelburg RA, Wiersum-Osselton JC, Brand A, van Tilburg C, Dinesh D, Dagger J, Dunn P, Brojer E, Letowska M, Maslanka K, Lachert E, Uhrynowska M, Zhiburt E, Palfi M, Berlin G, Frey BM, Puig Rovira L, Muñiz-Diaz E, Castro E, Chapman C, Green A, Massey E, Win N, Williamson L, Silliman CC, Chaffin DJ, Ambruso DR, Blumberg N, Tomasulo P, Land KJ, Norris PJ, Illoh OC, Davey RJ, Benjamin RJ, Eder AF, McLaughlin L, Kleinman S, Panzer S

Distinct roles of trauma and transfusion in induction of immune modulation after injury.

Transfusion

Jackman RP, Utter GH, Muench MO, Heitman JW, Munz MM, Jackman RW, Biswas HH, Rivers RM, Tobler LH, Busch MP, Norris PJ

Sensitive detection assays for influenza RNA do not reveal viremia in US blood donors.

The Journal of infectious diseases

Stramer SL, Collins C, Nugent T, Wang X, Fuschino M, Heitman JW, Law J, Krysztof DE, Kiely N, Todd D, Vermeulen NM, Harrington K, Kamel H, Kelvin DJ, Busch MP, St George K, Hewlett IK, Linnen JM, Norris PJ

Expansion of CD8+ T cells lacking Sema4D/CD100 during HIV-1 infection identifies a subset of T cells with decreased functional capacity.

Blood

Eriksson EM, Milush JM, Ho EL, Batista MD, Holditch SJ, Keh CE, Norris PJ, Keating SM, Deeks SG, Hunt PW, Martin JN, Rosenberg MG, Hecht FM, Nixon DF

Transfusion-related acute lung injury: incidence and risk factors.

Blood

Toy P, Gajic O, Bacchetti P, Looney MR, Gropper MA, Hubmayr R, Lowell CA, Norris PJ, Murphy EL, Weiskopf RB, Wilson G, Koenigsberg M, Lee D, Schuller R, Wu P, Grimes B, Gandhi MJ, Winters JL, Mair D, Hirschler N, Sanchez Rosen R, Matthay MA

Prevention of Alloimmunization and Induction of Partial Tolerance Following Transfusion with Pathogen Reduced Platelets in Mice.

Blood

Rachael P. Jackman, Marcus O. Muench, John W. Heitman, Susanne Marschner, Raymond P. Goodrich, Philip J. Norris

RBC-Derived Microparticles Evolve Over RBC Storage Time and Boost T Cell Mitogen Responses.

Blood

Ali Danesh, Jacqueline Law, John W. Heitman, Philip J Norris

The effect of HIV infection and HAART on inflammatory biomarkers in a population-based cohort of women.

AIDS (London, England)

Keating SM, Golub ET, Nowicki M, Young M, Anastos K, Crystal H, Cohen MH, Zhang J, Greenblatt RM, Desai S, Wu S, Landay AL, Gange SJ, Norris PJ

Identifying the early post-HIV antibody seroconversion period.

The Journal of infectious diseases

Hecht FM, Wellman R, Busch MP, Pilcher CD, Norris PJ, Margolick JB, Collier AC, Little SJ, Markowitz M, Routy JP, Holte S

Association between HLA class I and class II alleles and the outcome of West Nile virus infection: an exploratory study.

PloS one

Lanteri MC, Kaidarova Z, Peterson T, Cate S, Custer B, Wu S, Agapova M, Law JP, Bielawny T, Plummer F, Tobler LH, Loeb M, Busch MP, Bramson J, Luo M, Norris PJ

Multisite comparison of high-sensitivity multiplex cytokine assays.

Clinical and vaccine immunology : CVI

Breen EC, Reynolds SM, Cox C, Jacobson LP, Magpantay L, Mulder CB, Dibben O, Margolick JB, Bream JH, Sambrano E, Martínez-Maza O, Sinclair E, Borrow P, Landay AL, Rinaldo CR, Norris PJ

Cross-sectional detection of acute HIV infection: timing of transmission, inflammation and antiretroviral therapy.

PloS one

Gay C, Dibben O, Anderson JA, Stacey A, Mayo AJ, Norris PJ, Kuruc JD, Salazar-Gonzalez JF, Li H, Keele BF, Hicks C, Margolis D, Ferrari G, Haynes B, Swanstrom R, Shaw GM, Hahn BH, Eron JJ, Borrow P, Cohen MS

Immune and Genetic Correlates of Vaccine Protection Against Mucosal Infection by SIV in Monkeys.

Science translational medicine

Letvin NL, Rao SS, Montefiori DC, Seaman MS, Sun Y, Lim SY, Yeh WW, Asmal M, Gelman RS, Shen L, Whitney JB, Seoighe C, Lacerda M, Keating S, Norris PJ, Hudgens MG, Gilbert PB, Buzby AP, Mach LV, Zhang J, Balachandran H, Shaw GM, Schmidt SD, Todd JP, Dodson A, Mascola JR, Nabel GJ

[West Nile virus - I. conquest of the West].

Medecine sciences : M/S

Lanteri MC, Assal A, Norris PJ, Busch MP

[West Nile virus. II. Immunopathophysiology in humans].

Medecine sciences : M/S

Lanteri MC, Diamond MS, Norris PJ, Busch MP

A murine model of the immune responses to trauma and transfusion (169.36).

The Journal of Immunology

Rachael Jackman, Marcus Muench, John Heitman, Garth Utter, Michael Busch, Philip Norris

Properties of stored red blood cells: understanding immune and vascular reactivity.

Transfusion

Spinella PC, Sparrow RL, Hess JR, Norris PJ

Establishing assay cutoffs for HLA antibody screening of apheresis donors.

Transfusion

Carrick DM, Norris PJ, Endres RO, Pandey S, Kleinman SH, Wright D, Sun Y, Busch MP

A low T regulatory cell response may contribute to both viral control and generalized immune activation in HIV controllers.

PloS one

Hunt PW, Landay AL, Sinclair E, Martinson JA, Hatano H, Emu B, Norris PJ, Busch MP, Martin JN, Brooks C, McCune JM, Deeks SG

Effects of blood sample age at time of separation on measured cytokine concentrations in human plasma.

Clinical and vaccine immunology : CVI

Jackman RP, Utter GH, Heitman JW, Hirschkorn DF, Law JP, Gefter N, Busch MP, Norris PJ

Agreement among HLA antibody detection assays is higher in ever-pregnant donors and improved using a consensus cutoff.

Transfusion

Carrick DM, Johnson B, Kleinman SH, Vorhaben R, Chance SC, Lee JH, Roback JD, Pandey S, Sun Y, Busch MP, Norris PJ

The frequency and specificity of human neutrophil antigen antibodies in a blood donor population.

Transfusion

Gottschall JL, Triulzi DJ, Curtis B, Kakaiya RM, Busch MP, Norris PJ, Glynn SA, Carrick D, Wright DJ, Kleinman S

Evidence of persistent low-level viremia in long-term HAART-suppressed, HIV-infected individuals.

AIDS (London, England)

Hatano H, Delwart EL, Norris PJ, Lee TH, Neilands TB, Kelley CF, Hunt PW, Hoh R, Linnen JM, Martin JN, Busch MP, Deeks SG

CD57 defines a functionally distinct population of mature NK cells in the human CD56dimCD16+ NK-cell subset.

Blood

Lopez-Vergès S, Milush JM, Pandey S, York VA, Arakawa-Hoyt J, Pircher H, Norris PJ, Nixon DF, Lanier LL

Research and development.

Vox sanguinis

Devine DV, Reesink HW, Panzer S, Irving DO, Körmöczi GF, Mayr WR, Blais Y, Zhu Y, Qian K, Zhu Z, Greinacher A, Grazzini G, Pupella S, Catalano L, Vaglio S, Liumbruno GM, Smeenk JW, Josemans EA, Briët E, Letowska M, Lachert E, Antoniewicz-Papis J, Brojer E, Gulliksson H, Scott M, Williamson L, Prowse C, AuBuchon JP, López JA, Hoffman P, Busch MP, Norris PJ, Tomasulo P, Dodd RY

Low-dose mucosal simian immunodeficiency virus infection restricts early replication kinetics and transmitted virus variants in rhesus monkeys.

Journal of virology

Liu J, Keele BF, Li H, Keating S, Norris PJ, Carville A, Mansfield KG, Tomaras GD, Haynes BF, Kolodkin-Gal D, Letvin NL, Hahn BH, Shaw GM, Barouch DH

HIV+ elite controllers have low HIV-specific T-cell activation yet maintain strong, polyfunctional T-cell responses.

AIDS (London, England)

Owen RE, Heitman JW, Hirschkorn DF, Lanteri MC, Biswas HH, Martin JN, Krone MR, Deeks SG, Norris PJ

Elevated caspase-3 expression and T-cell activation in elite suppressors.

Journal of acquired immune deficiency syndromes (1999)

Ronquillo RE, Desai SN, Norris PJ, Golub ET, Greenblatt RM, Gange SJ, Landay AL

Potential inflammatory consequences in HIV controllers.

Retrovirology

Peter W Hunt, Priscilla Y Hsue, Elizabeth Sinclair, Alan L Landay, Jeffrey A Martinson, Hiroyu Hatano, Brinda Emu, Philip J Norris, Michael P Busch, Jeffrey N Martin, Cecily Brooks, Joseph M McCune, Steven G Deeks

Identification of specificities of antibodies against human leukocyte antigens in blood donors.

Transfusion

Endres RO, Kleinman SH, Carrick DM, Steele WR, Wright DJ, Norris PJ, Triulzi D, Kakaiya R, Busch MP

Prevalence of HLA antibodies in remotely transfused or alloexposed volunteer blood donors.

Transfusion

Kakaiya RM, Triulzi DJ, Wright DJ, Steele WR, Kleinman SH, Busch MP, Norris PJ, Hillyer CD, Gottschall JL, Rios JA, Carey P, Glynn SA

A novel human CD4+ T-cell inducer subset with potent immunostimulatory properties.

European journal of immunology

Ndhlovu LC, Leal FE, Eccles-James IG, Jha AR, Lanteri M, Norris PJ, Barbour JD, Wachter DJ, Andersson J, Taskén K, Torheim EA, Aandahl EM, Kallas EG, Nixon DF

The importance of Foxp3 antibody and fixation/permeabilization buffer combinations in identifying CD4+CD25+Foxp3+ regulatory T cells.

Cytometry. Part A : the journal of the International Society for Analytical Cytology

Law JP, Hirschkorn DF, Owen RE, Biswas HH, Norris PJ, Lanteri MC

HIV-Selectest enzyme immunoassay and rapid test: ability to detect seroconversion following HIV-1 infection.

Journal of clinical microbiology

Khurana S, Norris PJ, Busch MP, Haynes BF, Park S, Sasono P, Mlisana K, Salim AK, Hecht FM, Mulenga J, Chomba E, Hunter E, Allen S, Nemo G, Rodriguez-Chavez IR, Margolick JB, Golding H

Kinetics of early T cell receptor signaling regulate the pathway of lytic granule delivery to the secretory domain.

Immunity

Beal AM, Anikeeva N, Varma R, Cameron TO, Vasiliver-Shamis G, Norris PJ, Dustin ML, Sykulev Y

Tregs control the development of symptomatic West Nile virus infection in humans and mice.

The Journal of clinical investigation

Lanteri MC, O'Brien KM, Purtha WE, Cameron MJ, Lund JM, Owen RE, Heitman JW, Custer B, Hirschkorn DF, Tobler LH, Kiely N, Prince HE, Ndhlovu LC, Nixon DF, Kamel HT, Kelvin DJ, Busch MP, Rudensky AY, Diamond MS, Norris PJ

OA011-04. Striking elevations in systemic and mucosal cytokine and chemokine levels in acute HIV-1 infection.

Retrovirology

A Stacey, P Norris, O Dibben, L Qin, M Cohen, C Gay, T Denny, P Borrow

The effect of previous pregnancy and transfusion on HLA alloimmunization in blood donors: implications for a transfusion-related acute lung injury risk reduction strategy.

Transfusion

Triulzi DJ, Kleinman S, Kakaiya RM, Busch MP, Norris PJ, Steele WR, Glynn SA, Hillyer CD, Carey P, Gottschall JL, Murphy EL, Rios JA, Ness PM, Wright DJ, Carrick D, Schreiber GB

CD57 defines a functionally unique subset of NK cells in humans (134.1).

The Journal of Immunology

Sandra Lopez-Verges, Jeffrey M Milush, Suchitra Pandey, Philip Norris, Douglas Nixon, Lewis L Lanier

Cytolytic synapses control effectiveness of target cell destruction by CTL (35.17).

The Journal of Immunology

Yuri Sykulev, Allison M Beal, Nadia Anikeeva, Rajat Varma, Thomas O Cameron, Philip Norris, Michael L Dustin

The importance of Foxp3 antibody and fixation/permeabilization buffer combinations in identifying CD4+CD25+Foxp3+ regulatory T cells.

Cytometry Part A

Jacqueline P. Law, Dale F. Hirschkorn, Rachel E. Owen, Hope H. Biswas, Philip J. Norris, Marion C. Lanteri

Long-term in vitro reactivity for human leukocyte antigen antibodies and comparison of detection using serum versus plasma.

Transfusion

Norris PJ, Lee JH, Carrick DM, Gottschall JL, Lebedeva M, de Castro BR, Kleinman SH, Busch MP

Evidence for persistent low-level viremia in individuals who control human immunodeficiency virus in the absence of antiretroviral therapy.

Journal of virology

Hatano H, Delwart EL, Norris PJ, Lee TH, Dunn-Williams J, Hunt PW, Hoh R, Stramer SL, Linnen JM, McCune JM, Martin JN, Busch MP, Deeks SG

Interferon and interferon-induced chemokine expression is associated with control of acute viremia in West Nile virus-infected blood donors.

The Journal of infectious diseases

Tobler LH, Cameron MJ, Lanteri MC, Prince HE, Danesh A, Persad D, Lanciotti RS, Norris PJ, Kelvin DJ, Busch MP

Protein kinase C theta regulates stability of the peripheral adhesion ring junction and contributes to the sensitivity of target cell lysis by CTL.

Journal of immunology (Baltimore, Md. : 1950)

Beal AM, Anikeeva N, Varma R, Cameron TO, Norris PJ, Dustin ML, Sykulev Y

Virus and antibody dynamics in acute west nile virus infection.

The Journal of infectious diseases

Busch MP, Kleinman SH, Tobler LH, Kamel HT, Norris PJ, Walsh I, Matud JL, Prince HE, Lanciotti RS, Wright DJ, Linnen JM, Caglioti S

Suppression of HIV-1 plasma viral load below detection preserves IL-17 producing T cells in HIV-1 infection.

AIDS (London, England)

Ndhlovu LC, Chapman JM, Jha AR, Snyder-Cappione JE, Pagán M, Leal FE, Boland BS, Norris PJ, Rosenberg MG, Nixon DF

Comprehensive analysis of west nile virus-specific T cell responses in humans.

The Journal of infectious diseases

Lanteri MC, Heitman JW, Owen RE, Busch T, Gefter N, Kiely N, Kamel HT, Tobler LH, Busch MP, Norris PJ

Nanoparticle-Based biobarcode amplification assay (BCA) for sensitive and early detection of human immunodeficiency type 1 capsid (p24) antigen.

Journal of acquired immune deficiency syndromes (1999)

Tang S, Zhao J, Storhoff JJ, Norris PJ, Little RF, Yarchoan R, Stramer SL, Patno T, Domanus M, Dhar A, Mirkin CA, Hewlett IK

Loss of T cell responses following long-term cryopreservation.

Journal of immunological methods

Owen RE, Sinclair E, Emu B, Heitman JW, Hirschkorn DF, Epling CL, Tan QX, Custer B, Harris JM, Jacobson MA, McCune JM, Martin JN, Hecht FM, Deeks SG, Norris PJ

Influenza viremia and the potential for blood-borne transmission.

Transfusion

Likos AM, Kelvin DJ, Cameron CM, Rowe T, Kuehnert MJ, Norris PJ

From a single viral peptide epitope to effective lysis of target cells by CTL (87.50).

The Journal of Immunology

Yuri Sykulev, Nadia Anikeeva, Allison Beal, Gaia Vasiliver, Rajat Varma, Philip J Norris, Hedi Mattoussi, Michael L Dustin

Elevations in IL-10, TNF-alpha, and IFN-gamma from the earliest point of HIV Type 1 infection.

AIDS research and human retroviruses

Norris PJ, Pappalardo BL, Custer B, Spotts G, Hecht FM, Busch MP

The antigenic determinants on HIV p24 for CD4+ T cell inhibiting antibodies as determined by limited proteolysis, chemical modification, and mass spectrometry.

Journal of the American Society for Mass Spectrometry

Williams JG, Tomer KB, Hioe CE, Zolla-Pazner S, Norris PJ

The effects of early antiretroviral therapy and its discontinuation on the HIV-specific antibody response.

AIDS research and human retroviruses

Killian MS, Norris PJ, Rawal BD, Lebedeva M, Hecht FM, Levy JA, Busch MP

Antagonism of HIV-specific CD4+ T cells by C-terminal truncation of a minimum epitope.

Molecular immunology

Norris PJ, Stone JD, Anikeeva N, Heitman JW, Wilson IC, Hirschkorn DF, Clark MJ, Moffett HF, Cameron TO, Sykulev Y, Stern LJ, Walker BD

Modified anthrax fusion proteins deliver HIV antigens through MHC Class I and II pathways.

Vaccine

McEvers K, Elrefaei M, Norris P, Deeks S, Martin J, Lu Y, Cao H

A hairpin turn in a class II MHC-bound peptide orients residues outside the binding groove for T cell recognition.

Proceedings of the National Academy of Sciences of the United States of America

Zavala-Ruiz Z, Strug I, Walker BD, Norris PJ, Stern LJ

Beyond help: direct effector functions of human immunodeficiency virus type 1-specific CD4(+) T cells.

Journal of virology

Norris PJ, Moffett HF, Yang OO, Kaufmann DE, Clark MJ, Addo MM, Rosenberg ES

Heat shock protein-mediated cross-presentation of exogenous HIV antigen on HLA class I and class II.

Journal of immunology (Baltimore, Md. : 1950)

SenGupta D, Norris PJ, Suscovich TJ, Hassan-Zahraee M, Moffett HF, Trocha A, Draenert R, Goulder PJ, Binder RJ, Levey DL, Walker BD, Srivastava PK, Brander C

Comprehensive analysis of human immunodeficiency virus type 1-specific CD4 responses reveals marked immunodominance of gag and nef and the presence of broadly recognized peptides.

Journal of virology

Kaufmann DE, Bailey PM, Sidney J, Wagner B, Norris PJ, Johnston MN, Cosimi LA, Addo MM, Lichterfeld M, Altfeld M, Frahm N, Brander C, Sette A, Walker BD, Rosenberg ES

Fine specificity and cross-clade reactivity of HIV type 1 Gag-specific CD4+ T cells.

AIDS research and human retroviruses

Norris PJ, Moffett HF, Brander C, Allen TM, O'Sullivan KM, Cosimi LA, Kaufmann DE, Walker BD, Rosenberg ES

Labeling antigen-specific CD4(+) T cells with class II MHC oligomers.

Journal of immunological methods

Cameron TO, Norris PJ, Patel A, Moulon C, Rosenberg ES, Mellins ED, Wedderburn LR, Stern LJ

CD4(+) T helper cells and the role they play in viral control.

Journal of molecular medicine (Berlin, Germany)

Norris PJ, Rosenberg ES

Inhibition of human immunodeficiency virus type 1 gp120 presentation to CD4 T cells by antibodies specific for the CD4 binding domain of gp120.

Journal of virology

Hioe CE, Tuen M, Chien PC, Jones G, Ratto-Kim S, Norris PJ, Moretto WJ, Nixon DF, Gorny MK, Zolla-Pazner S

Multiple effector functions mediated by human immunodeficiency virus-specific CD4(+) T-cell clones.

Journal of virology

Norris PJ, Sumaroka M, Brander C, Moffett HF, Boswell SL, Nguyen T, Sykulev Y, Walker BD, Rosenberg ES

Cellular immune response to human immunodeficiency virus.

AIDS (London, England)

Norris PJ, Rosenberg ES

Regional distribution of cytochrome P450 2D1 in the rat central nervous system.

The Journal of comparative neurology

Norris PJ, Hardwick JP, Emson PC