Cytotherapy

Development of a robotic cluster for automated and scalable cell therapy manufacturing.

Cytotherapy

Alice Melocchi, Brigitte Schmittlein, Alexis L. Jones, Yasmine Ainane, Ali Rizvi, Darius Chan, Elaine Dickey, Kelsey Pool, Kenny Harsono, Dorothy Szymkiewicz, Umberto Scarfogliero, Varun Bhatia, Amlesh Sivanantham, Nadia Kreciglowa, Allison Hunter, Miguel Gomez, Adrian Tanner, Marco Uboldi, Arpit Batish, Joanna Balcerek, Mariella Kutova-Stoilova, Sreenivasan Paruthiyil, Luis A. Acevedo, Rachel Stadnitskiy, Sabrina Carmichael, Holger Aulbach, Matthew Hewitt, Xavier De Mollerat Du Jeu, Benedetta di Robilant, Federico Parietti, Jonathan H. Esensten

Local manufacturing processes contribute to variability in human mesenchymal stromal cell expansion while growth media supplements contribute to variability in gene expression and cell function: a Biomedical Excellence for Safer Transfusion (BEST) collabo

Cytotherapy

Shaz BH, Schäfer R, Fontaine MJ, Norris PJ, McKenna DH, Jin P, Reems JA, Stroncek D, Tanashi M, Marks D, Geng H, Pati S, for Biomedical Excellence for Safer Transfusion (BEST)

41 Mesenchymal Stem/Stromal Cells: LOCAL MANUFACTURING PROCESSES CONTRIBUTE TO VARIABILITY IN HUMAN MESENCHYMAL STROMAL CELL (MSC) EXPANSION WHILE GROWTH MEDIA SUPPLEMENTS CONTRIBUTE TO VARIABILITY IN GENE EXPRESSION AND CELL FUNCTION. THE BEST COLLABORAT

Cytotherapy

B. Shaz, R. Schäfer, M. Fontaine, P. Norris, D. McKenna, B. Miyazawa, P. Jin, J. Reems, D. Stroncek, M. Takanashi, D.C. Marks, H. Geng, S. Pati

Reduced dimethyl sulfoxide concentrations successfully cryopreserve human hematopoietic stem cells with multi-lineage long-term engraftment ability in mice.

Cytotherapy

Gilfanova R, Auclair KM, Hui A, Norris PJ, Muench MO

Processing laboratory considerations for multi-center cellular therapy clinical trials: a report from the Consortium for Pediatric Cellular Immunotherapy.

Cytotherapy

Lindgren C, Leinbach A, Annis J, Tanna J, Zhang N, Esensten JH, Hanley PJ

Development of a large-scale H3.3K27M-specific TCR-transduced T cell manufacturing method for adoptive cell therapy in HLA-A2+ patients with diffuse midline glioma.

Cytotherapy

K. Okada, A. Nguyen, P. Watchmaker, J. Xu, F. Ramsdell, J.H. Esensten, L.H. Butterfield, H. Okada

319 Developing a database to track critical parameters for clinical regulatory T cell manufacturing.

Cytotherapy

B.R. Shy, J. Whitman, A.L. Putnam, A. Lares, Q. Tang, J.H. Esensten

66 Low levels of EBV detected by PCR during manufacturing of clinical-grade stimulated B cells despite treatment with antiviral drugs.

Cytotherapy

K. Lee, Q. Tang, J.H. Esensten

Peptide-pulsed dendritic cell vaccination targeting interleukin-13 receptor a2 chain in recurrent malignant glioma patients with HLA-A24/A02 allele.

Cytotherapy

Iwami K, Shimato S, Ohno M, Okada H, Nakahara N, Sato Y, Yoshida J, Suzuki S, Nishikawa H, Shiku H, Natsume A, Wakabayashi T