Sonja Schrepfer, MD, PhD

Professor
Surgery
+1 415 502-8742
Publications: 

Hypoimmune islets achieve insulin independence after allogeneic transplantation in a fully immunocompetent non-human primate.

Cell stem cell

Hu X, White K, Young C, Olroyd AG, Kievit P, Connolly AJ, Deuse T, Schrepfer S

Synthetic immune checkpoint engagers protect HLA-deficient iPSCs and derivatives from innate immune cell cytotoxicity.

Cell stem cell

Gravina A, Tediashvili G, Zheng Y, Iwabuchi KA, Peyrot SM, Roodsari SZ, Gargiulo L, Kaneko S, Osawa M, Schrepfer S, Deuse T

Hypoimmune induced pluripotent stem cells survive long term in fully immunocompetent, allogeneic rhesus macaques.

Nature biotechnology

Hu X, White K, Olroyd AG, DeJesus R, Dominguez AA, Dowdle WE, Friera AM, Young C, Wells F, Chu EY, Ito CE, Krishnapura H, Jain S, Ankala R, McGill TJ, Lin A, Egenberger K, Gagnon A, Michael Rukstalis J, Hogrebe NJ, Gattis C, Basco R, Millman JR, Kievit P, Davis MM, Lanier LL, Connolly AJ, Deuse T, Schrepfer S

Human hypoimmune primary pancreatic islets avoid rejection and autoimmunity and alleviate diabetes in allogeneic humanized mice.

Science translational medicine

Hu X, Gattis C, Olroyd AG, Friera AM, White K, Young C, Basco R, Lamba M, Wells F, Ankala R, Dowdle WE, Lin A, Egenberger K, Rukstalis JM, Millman JR, Connolly AJ, Deuse T, Schrepfer S

Hypoimmune anti-CD19 chimeric antigen receptor T cells provide lasting tumor control in fully immunocompetent allogeneic humanized mice.

Nature communications

Hu X, Manner K, DeJesus R, White K, Gattis C, Ngo P, Bandoro C, Tham E, Chu EY, Young C, Wells F, Basco R, Friera A, Kangeyan D, Beauchesne P, Dowdle WE, Deuse T, Fry TJ, Foster AE, Schrepfer S

Protection of cell therapeutics from antibody-mediated killing by CD64 overexpression.

Nature biotechnology

Gravina A, Tediashvili G, Rajalingam R, Quandt Z, Deisenroth C, Schrepfer S, Deuse T

Author Correction: Hypoimmunogenic derivatives of induced pluripotent stem cells evade immune rejection in fully immunocompetent allogeneic recipients.

Nature biotechnology

Deuse T, Hu X, Gravina A, Wang D, Tediashvili G, De C, Thayer WO, Wahl A, Garcia JV, Reichenspurner H, Davis MM, Lanier LL, Schrepfer S

Hypoimmune induced pluripotent stem cell-derived cell therapeutics treat cardiovascular and pulmonary diseases in immunocompetent allogeneic mice.

Proceedings of the National Academy of Sciences of the United States of America

Deuse T, Tediashvili G, Hu X, Gravina A, Tamenang A, Wang D, Connolly A, Mueller C, Mallavia B, Looney MR, Alawi M, Lanier LL, Schrepfer S

Immunomodulation therapy using tolerogenic macrophages in a rodent model of pulmonary hypertension.

Stem cells and development

Guihaire J, Deuse T, Wang D, Spin JM, Blankenberg FG, Fadel E, Reichenspurner H, Schrepfer S

The SIRPα-CD47 immune checkpoint in NK cells.

The Journal of experimental medicine

Deuse T, Hu X, Agbor-Enoh S, Jang MK, Alawi M, Saygi C, Gravina A, Tediashvili G, Nguyen VQ, Liu Y, Valantine H, Lanier LL, Schrepfer S

Comprehensive Multi-omics Analysis Reveals Mitochondrial Stress as a Central Biological Hub for Spaceflight Impact.

Cell

da Silveira WA, Fazelinia H, Rosenthal SB, Laiakis EC, Kim MS, Meydan C, Kidane Y, Rathi KS, Smith SM, Stear B, Ying Y, Zhang Y, Foox J, Zanello S, Crucian B, Wang D, Nugent A, Costa HA, Zwart SR, Schrepfer S, Elworth RAL, Sapoval N, Treangen T, MacKay M, Gokhale NS, Horner SM, Singh LN, Wallace DC, Willey JS, Schisler JC, Meller R, McDonald JT, Fisch KM, Hardiman G, Taylor D, Mason CE, Costes SV, Beheshti A

The H-Y Antigen in Embryonic Stem Cells Causes Rejection in Syngeneic Female Recipients.

Stem cells and development

Hu X, Kueppers ST, Kooreman NG, Gravina A, Wang D, Tediashvili G, Schlickeiser S, Frentsch M, Nikolaou C, Thiel A, Marcus S, Fuchs S, Velden J, Reichenspurner H, Volk HD, Deuse T, Schrepfer S

A Cryoinjury Model to Study Myocardial Infarction in the Mouse.

Journal of visualized experiments : JoVE

Wang D, Tediashvili G, Hu X, Gravina A, Marcus SG, Zhang H, Olgin JE, Deuse T, Schrepfer S

De novo mutations in mitochondrial DNA of iPSCs produce immunogenic neoepitopes in mice and humans.

Nature biotechnology

Deuse T, Hu X, Agbor-Enoh S, Koch M, Spitzer MH, Gravina A, Alawi M, Marishta A, Peters B, Kosaloglu-Yalcin Z, Yang Y, Rajalingam R, Wang D, Nashan B, Kiefmann R, Reichenspurner H, Valantine H, Weissman IL, Schrepfer S

Hypoimmunogenic derivatives of induced pluripotent stem cells evade immune rejection in fully immunocompetent allogeneic recipients.

Nature biotechnology

Deuse T, Hu X, Gravina A, Wang D, Tediashvili G, De C, Thayer WO, Wahl A, Garcia JV, Reichenspurner H, Davis MM, Lanier LL, Schrepfer S

Dead space ventilation promotes alveolar hypocapnia reducing surfactant secretion by altering mitochondrial function.

Thorax

Kiefmann M, Tank S, Tritt MO, Keller P, Heckel K, Schulte-Uentrop L, Olotu C, Schrepfer S, Goetz AE, Kiefmann R

Exosomal profiling in cardiac allograft rejection: Best basic science article in 2018.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation

Kulkarni HS, Diamond JM, Schrepfer S, Cantu E

No effect of thymosin beta-4 on the expression of the transcription factor Islet-1 in the adult murine heart.

Pharmacology research & perspectives

Weinberger F, Nicol P, Starbatty J, Stubbendorff M, Becher PM, Schrepfer S, Eschenhagen T

Sphingosine-1-phosphate receptor 1 regulates neointimal growth in a humanized model for restenosis.

Journal of vascular surgery

Braetz J, Becker A, Geissen M, Larena-Avellaneda A, Schrepfer S, Daum G

Optimization of oxygenation during ex vivo lung perfusion-Best basic science article in 2017.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation

Shaver CM, Diamond JM, Schrepfer S, Cantu E

Balloon-based Injury to Induce Myointimal Hyperplasia in the Mouse Abdominal Aorta.

Journal of visualized experiments : JoVE

Tediashvili G, Wang D, Reichenspurner H, Deuse T, Schrepfer S

Opportunities for Lung Repair and Regeneration: An Overview.

Annals of the American Thoracic Society

Schrepfer S

Thalidomide treatment prevents chronic graft rejection after aortic transplantation in rats - an experimental study.

Transplant international : official journal of the European Society for Organ Transplantation

Miller KK, Wang D, Hu X, Hua X, Deuse T, Neofytou E, Renne T, Velden J, Reichenspurner H, Schrepfer S, Bernstein D

Differences in Vascular Response between Balloon Overstretch and Stent Overexpansion in Nonatherosclerotic Porcine Coronary Arteries.

Comparative medicine

Mitsutake Y, Reifart J, Pyun WB, Lyons JK, Deuse T, Schrepfer S, Ikeno F

The ubiquitin-proteasome system: A potential therapeutic target for heart failure.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation

Barac YD, Emrich F, Krutzwakd-Josefson E, Schrepfer S, Sampaio LC, Willerson JT, Robbins RC, Ciechanover A, Mohr FW, Aravot D, Taylor DA

Vein Interposition Model: A Suitable Model to Study Bypass Graft Patency.

Journal of visualized experiments : JoVE

Wang D, Tediashvili G, Pecha S, Reichenspurner H, Deuse T, Schrepfer S

Orthotopic tracheal transplantation using human bronchus: an original xenotransplant model of obliterative airway disorder.

Transplant international : official journal of the European Society for Organ Transplantation

Guihaire J, Itagaki R, Stubbendorff M, Hua X, Deuse T, Ullrich S, Fadel E, Dorfmüller P, Robbins RC, Reichenspurner H, Schumacher U, Schrepfer S

miR-126: a potential new key player in hypoxia and reperfusion?

Annals of translational medicine

Guenther SP, Schrepfer S

The Selective JAK1/3-Inhibitor R507 Mitigates Obliterative Airway Disease Both With Systemic Administration and Aerosol Inhalation.

Transplantation

Deuse T, Hua X, Stubbendorff M, Spin JM, Neofytou E, Taylor V, Chen Y, Park G, Fink JB, Renne T, Kiefmann M, Kiefmann R, Reichenspurner H, Robbins RC, Schrepfer S

"Bioengineered lungs" Best science paper in JHLT 2014-2015.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation

Schrepfer S, Cantu E, Gandy K, Baan CC, West LJ

miR-21 promotes fibrosis in an acute cardiac allograft transplantation model.

Cardiovascular research

Gupta SK, Itagaki R, Zheng X, Batkai S, Thum S, Ahmad F, Van Aelst LN, Sharma A, Piccoli MT, Weinberger F, Fiedler J, Heuser M, Heymans S, Falk CS, Förster R, Schrepfer S, Thum T

Alagebrium inhibits neointimal hyperplasia and restores distributions of wall shear stress by reducing downstream vascular resistance in obese and diabetic rats.

American journal of physiology. Heart and circulatory physiology

Wang H, Weihrauch D, Kersten JR, Toth JM, Passerini AG, Rajamani A, Schrepfer S, LaDisa JF

Local MicroRNA Modulation Using a Novel Anti-miR-21-Eluting Stent Effectively Prevents Experimental In-Stent Restenosis.

Arteriosclerosis, thrombosis, and vascular biology

Wang D, Deuse T, Stubbendorff M, Chernogubova E, Erben RG, Eken SM, Jin H, Li Y, Busch A, Heeger CH, Behnisch B, Reichenspurner H, Robbins RC, Spin JM, Tsao PS, Schrepfer S, Maegdefessel L

Immunobiology of fibrin-based engineered heart tissue.

Stem cells translational medicine

Conradi L, Schmidt S, Neofytou E, Deuse T, Peters L, Eder A, Hua X, Hansen A, Robbins RC, Beygui RE, Reichenspurner H, Eschenhagen T, Schrepfer S

Impaired Endothelial Regeneration Through Human Parvovirus B19-Infected Circulating Angiogenic Cells in Patients With Cardiomyopathy.

The Journal of infectious diseases

Schmidt-Lucke C, Zobel T, Schrepfer S, Kuhl U, Wang D, Klingel K, Becher PM, Fechner H, Pozzuto T, Van Linthout S, Lassner D, Spillmann F, Escher F, Holinski S, Volk HD, Schultheiss HP, Tschope C

Erratum: miR-24 limits aortic vascular inflammation and murine abdominal aneurysm development.

Nature communications

Maegdefessel L, Spin JM, Raaz U, Eken SM, Toh R, Azuma J, Adam M, Nakagami F, Heymann HM, Chernogubova E, Jin H, Roy J, Hultgren R, Caidahl K, Schrepfer S, Hamsten A, Eriksson P, McConnell MV, Dalman RL, Tsao PS

SCNT-derived ESCs with mismatched mitochondria trigger an immune response in allogeneic hosts.

Cell stem cell

Deuse T, Wang D, Stubbendorff M, Itagaki R, Grabosch A, Greaves LC, Alawi M, Grünewald A, Hu X, Hua X, Velden J, Reichenspurner H, Robbins RC, Jaenisch R, Weissman IL, Schrepfer S

miR-24 limits aortic vascular inflammation and murine abdominal aneurysm development.

Nature communications

Maegdefessel L, Spin JM, Raaz U, Eken SM, Toh R, Azuma J, Adam M, Nakagami F, Nagakami F, Heymann HM, Chernogubova E, Chernugobova E, Jin H, Roy J, Hultgren R, Caidahl K, Schrepfer S, Hamsten A, Eriksson P, McConnell MV, Dalman RL, Tsao PS

Inducing myointimal hyperplasia versus atherosclerosis in mice: an introduction of two valid models.

Journal of visualized experiments : JoVE

Stubbendorff M, Hua X, Deuse T, Ali Z, Reichenspurner H, Maegdefessel L, Robbins RC, Schrepfer S

Dichloroacetate prevents restenosis in preclinical animal models of vessel injury.

Nature

Deuse T, Hua X, Wang D, Maegdefessel L, Heeren J, Scheja L, Bolaños JP, Rakovic A, Spin JM, Stubbendorff M, Ikeno F, Länger F, Zeller T, Schulte-Uentrop L, Stoehr A, Itagaki R, Haddad F, Eschenhagen T, Blankenberg S, Kiefmann R, Reichenspurner H, Velden J, Klein C, Yeung A, Robbins RC, Tsao PS, Schrepfer S

Immunological properties of extraembryonic human mesenchymal stromal cells derived from gestational tissue.

Stem cells and development

Stubbendorff M, Deuse T, Hua X, Phan TT, Bieback K, Atkinson K, Eiermann TH, Velden J, Schröder C, Reichenspurner H, Robbins RC, Volk HD, Schrepfer S

Small animal models of experimental obliterative bronchiolitis.

American journal of respiratory cell and molecular biology

Jungraithmayr W, Jang JH, Schrepfer S, Inci I, Weder W

The potassium channel KCa3.1 as new therapeutic target for the prevention of obliterative airway disease.

Transplantation

Hua X, Deuse T, Chen YJ, Wulff H, Stubbendorff M, Köhler R, Miura H, Länger F, Reichenspurner H, Robbins RC, Schrepfer S

Significant reduction of acute cardiac allograft rejection by selective janus kinase-1/3 inhibition using R507 and R545.

Transplantation

Deuse T, Hua X, Taylor V, Stubbendorff M, Baluom M, Chen Y, Park G, Velden J, Streichert T, Reichenspurner H, Robbins RC, Schrepfer S

Effects of intracoronary CD34+ stem cell transplantation in nonischemic dilated cardiomyopathy patients: 5-year follow-up.

Circulation research

Vrtovec B, Poglajen G, Lezaic L, Sever M, Domanovic D, Cernelc P, Socan A, Schrepfer S, Torre-Amione G, Haddad F, Wu JC

Human internal mammary artery (IMA) transplantation and stenting: a human model to study the development of in-stent restenosis.

Journal of visualized experiments : JoVE

Hua X, Deuse T, Michelakis ED, Haromy A, Tsao PS, Maegdefessel L, Erben RG, Bergow C, Behnisch BB, Reichenspurner H, Robbins RC, Schrepfer S

Localization of Islet-1-positive cells in the healthy and infarcted adult murine heart.

Circulation research

Weinberger F, Mehrkens D, Friedrich FW, Stubbendorff M, Hua X, Müller JC, Schrepfer S, Evans SM, Carrier L, Eschenhagen T

Human leukocyte antigen I knockdown human embryonic stem cells induce host ignorance and achieve prolonged xenogeneic survival.

Circulation

Deuse T, Seifert M, Phillips N, Fire A, Tyan D, Kay M, Tsao PS, Hua X, Velden J, Eiermann T, Volk HD, Reichenspurner H, Robbins RC, Schrepfer S

Immunobiology of naïve and genetically modified HLA-class-I-knockdown human embryonic stem cells.

Journal of cell science

Deuse T, Seifert M, Phillips N, Fire A, Tyan D, Kay M, Tsao PS, Hua X, Velden J, Eiermann T, Volk HD, Reichenspurner H, Robbins RC, Schrepfer S

Assessment of physiologic natural killer cell cytotoxicity in vitro.

Human immunology

Duske H, Sputtek A, Binder T, Kröger N, Schrepfer S, Eiermann T

Peptide ligands incorporated into the threefold spike capsid domain to re-direct gene transduction of AAV8 and AAV9 in vivo.

PloS one

Michelfelder S, Varadi K, Raupp C, Hunger A, Körbelin J, Pahrmann C, Schrepfer S, Müller OJ, Kleinschmidt JA, Trepel M

Bioluminescence imaging for assessment of immune responses following implantation of engineered heart tissue (EHT).

Journal of visualized experiments : JoVE

Conradi L, Pahrmann C, Schmidt S, Deuse T, Hansen A, Eder A, Reichenspurner H, Robbins RC, Eschenhagen T, Schrepfer S

Prevention of transplant coronary artery disease by prenylation inhibitors.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation

Stein W, Schrepfer S, Itoh S, Kimura N, Velotta J, Palmer O, Bartos J, Wang X, Robbins RC, Fischbein MP

Orthotopic aortic transplantation: a rat model to study the development of chronic vasculopathy.

Journal of visualized experiments : JoVE

Stubbendorff M, Deuse T, Hammel A, Robbins RC, Reichenspurner H, Schrepfer S

Immunogenicity and immunomodulatory properties of umbilical cord lining mesenchymal stem cells.

Cell transplantation

Deuse T, Stubbendorff M, Tang-Quan K, Phillips N, Kay MA, Eiermann T, Phan TT, Volk HD, Reichenspurner H, Robbins RC, Schrepfer S

Sustained inhibition of epsilon protein kinase C inhibits vascular restenosis after balloon injury and stenting.

Circulation

Deuse T, Koyanagi T, Erben RG, Hua X, Velden J, Ikeno F, Reichenspurner H, Robbins RC, Mochly-Rosen D, Schrepfer S

Non-volume-loaded heart provides a more relevant heterotopic transplantation model.

Transplant immunology

Tang-Quan KR, Bartos J, Deuse T, Churchill E, Schäfer H, Reichenspurner H, Mochly-Rosen D, Robbins RC, Schrepfer S

Heterotopic and orthotopic tracheal transplantation in mice used as models to study the development of obliterative airway disease.

Journal of visualized experiments : JoVE

Hua X, Deuse T, Tang-Quan KR, Robbins RC, Reichenspurner H, Schrepfer S

Mechanisms behind local immunosuppression using inhaled tacrolimus in preclinical models of lung transplantation.

American journal of respiratory cell and molecular biology

Deuse T, Blankenberg F, Haddad M, Reichenspurner H, Phillips N, Robbins RC, Schrepfer S

LAD-ligation: a murine model of myocardial infarction.

Journal of visualized experiments : JoVE

Kolk MV, Meyberg D, Deuse T, Tang-Quan KR, Robbins RC, Reichenspurner H, Schrepfer S

Poor functional recovery after transplantation of diabetic bone marrow stem cells in ischemic myocardium.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation

Govaert JA, Swijnenburg RJ, Schrepfer S, Xie X, van der Bogt KE, Hoyt G, Stein W, Ransohoff KJ, Robbins RC, Wu JC

Hepatocyte growth factor or vascular endothelial growth factor gene transfer maximizes mesenchymal stem cell-based myocardial salvage after acute myocardial infarction.

Circulation

Deuse T, Peter C, Fedak PW, Doyle T, Reichenspurner H, Zimmermann WH, Eschenhagen T, Stein W, Wu JC, Robbins RC, Schrepfer S

Imaging in-stent restenosis: an inexpensive, reliable, and rapid preclinical model.

Journal of visualized experiments : JoVE

Deuse T, Ikeno F, Robbins RC, Schrepfer S

A novel JAK3 inhibitor, R348, attenuates chronic airway allograft rejection.

Transplantation

Velotta JB, Deuse T, Haddad M, Masuda E, Park G, Carroll D, Taylor V, Robbins RC, Schrepfer S

Comparison of transplantation of adipose tissue- and bone marrow-derived mesenchymal stem cells in the infarcted heart.

Transplantation

van der Bogt KE, Schrepfer S, Yu J, Sheikh AY, Hoyt G, Govaert JA, Velotta JB, Contag CH, Robbins RC, Wu JC

In vivo imaging of embryonic stem cells reveals patterns of survival and immune rejection following transplantation.

Stem cells and development

Swijnenburg RJ, Schrepfer S, Cao F, Pearl JI, Xie X, Connolly AJ, Robbins RC, Wu JC

Comparison of different adult stem cell types for treatment of myocardial ischemia.

Circulation

van der Bogt KE, Sheikh AY, Schrepfer S, Hoyt G, Cao F, Ransohoff KJ, Swijnenburg RJ, Pearl J, Lee A, Fischbein M, Contag CH, Robbins RC, Wu JC

Immunosuppressive therapy mitigates immunological rejection of human embryonic stem cell xenografts.

Proceedings of the National Academy of Sciences of the United States of America

Swijnenburg RJ, Schrepfer S, Govaert JA, Cao F, Ransohoff K, Sheikh AY, Haddad M, Connolly AJ, Davis MM, Robbins RC, Wu JC

Novel immunosuppression: R348, a JAK3- and Syk-inhibitor attenuates acute cardiac allograft rejection.

Transplantation

Deuse T, Velotta JB, Hoyt G, Govaert JA, Taylor V, Masuda E, Herlaar E, Park G, Carroll D, Pelletier MP, Robbins RC, Schrepfer S

Prevention and inhibition but not reversion of chronic allograft vasculopathy by FK778.

Transplantation

Deuse T, Hoyt G, Koyanagi T, Robbins RC, Schrepfer S

Introducing the first polymer-free leflunomide eluting stent.

Atherosclerosis

Deuse T, Erben RG, Ikeno F, Behnisch B, Boeger R, Connolly AJ, Reichenspurner H, Bergow C, Pelletier MP, Robbins RC, Schrepfer S

Inhibition of aldehyde dehydrogenase type 2 attenuates vasodilatory action of nitroglycerin in human veins.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Huellner MW, Schrepfer S, Weyand M, Weiner H, Wimplinger I, Eschenhagen T, Rau T

Failed induction of heme oxygenase 1 in endothelial cells exposed to the hemoglobin based oxygen carrier Oxyglobin.

Artificial cells, blood substitutes, and immobilization biotechnology

Rempf C, Ritter A, Schrepfer S, Freitag M, Standl T, Gottschalk A

Right atrial mass after primary repair of an atrial septal defect: thrombus masquerading as a myxoma.

The Annals of thoracic surgery

Sheikh AY, Schrepfer S, Stein W, West J, Lombard J, Burdon T, Pinsker B, Pelletier MP

Techniques for experimental heterotopic and orthotopic tracheal transplantations - When to use which model?

Transplant immunology

Deuse T, Schrepfer S, Reichenspurner H, Hoyt G, Fischbein MP, Robbins RC, Pelletier MP

Coincidence of aortic valve stenosis and regurgitation and multiple cardiac papillary fibroelastomas in a young male adult.

The Journal of thoracic and cardiovascular surgery

Sydow K, Schrepfer S, Franzen O, Detter C, Willems S, Meinertz T, Reichenspurner H

Simplified protocol to isolate, purify, and culture expand mesenchymal stem cells.

Stem cells and development

Schrepfer S, Deuse T, Lange C, Katzenberg R, Reichenspurner H, Robbins RC, Pelletier MP

Experimental orthotopic tracheal transplantation: The Stanford technique.

Microsurgery

Schrepfer S, Deuse T, Hoyt G, Sheikh AY, Hoffmann J, Reichenspurner H, Robbins RC, Pelletier MP

FK778 in experimental xenotransplantation: a detailed analysis of drug efficacy.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation

Schrepfer S, Deuse T, Koch-Nolte F, Krieger T, Haddad M, Schäfer H, Pelletier MP, Robbins RC, Reichenspurner H

Inhibition of restenosis development after mechanical injury: a new field of application for malononitrilamides?

Cardiology

Schrepfer S, Deuse T, Sultan KR, Haddad M, Böger R, Münzel T, Schäfer H, Pelletier MP, Robbins RC, Reichenspurner H

The selective estrogen receptor-beta agonist biochanin A shows vasculoprotective effects without uterotrophic activity.

Menopause (New York, N.Y.)

Schrepfer S, Deuse T, Münzel T, Schäfer H, Braendle W, Reichenspurner H

Heparins increase endothelial nitric oxide bioavailability by liberating vessel-immobilized myeloperoxidase.

Circulation

Baldus S, Rudolph V, Roiss M, Ito WD, Rudolph TK, Eiserich JP, Sydow K, Lau D, Szöcs K, Klinke A, Kubala L, Berglund L, Schrepfer S, Deuse T, Haddad M, Risius T, Klemm H, Reichenspurner HC, Meinertz T, Heitzer T

Sirolimus and FK778: a comparison of two anti-proliferative immunosuppressants for prevention of experimental obliterative airway disease.

Transplant international : official journal of the European Society for Organ Transplantation

Deuse T, Schrepfer S, Koch-Nolte F, Haddad M, Schäfer H, Detter C, Reichenspurner H

The phytoestrogen biochaninA weakens acute cardiac allograft rejection without affecting the reproductive system.

Transplant immunology

Schrepfer S, Deuse T, Schäfer H, Koch-Nolte F, Braendle W, Reichenspurner H

FK778 and tacrolimus prevent the development of obliterative airway disease after heterotopic rat tracheal transplantation.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation

Deuse T, Schrepfer S, Koch-Nolte F, Haddad M, Schwedhelm E, Böger R, Schäfer H, Detter C, Reichenspurner H

FK778, a novel immunosuppressive agent, reduces early adhesion molecule up-regulation and prolongs cardiac allograft survival.

Transplant international : official journal of the European Society for Organ Transplantation

Schrepfer S, Deuse T, Schäfer H, Reichenspurner H

FK778 attenuates lymphocyte-endothelium interaction after cardiac transplantation: in vivo and in vitro studies.

Transplantation

Deuse T, Schrepfer S, Schäfer H, Koch-Nolte F, Schwedhelm E, Böger RH, Reichenspurner H

Successful resection of a symptomatic right ventricular lipoma.

The Annals of thoracic surgery

Schrepfer S, Deuse T, Detter C, Treede H, Koops A, Boehm DH, Willems S, Lacour-Gayet F, Reichenspurner H

New technique for chest opening in mice: U-sternotomy.

Microsurgery

Schrepfer S, Deuse T, Reichenspurner H

Myoblasts survive intracardiac transfer and divide further after transplantation.

The heart surgery forum

Gulbins H, Schrepfer S, Uhlig A, Goldemund A, Oberhoffer M, Reichenspurner H, Meiser B, Reichart B