Petros Giannikopoulos, MD

Assistant Adjunct Professor

Laboratory Medicine

+1 415 353-7359

Publications:

Patient-Specific In Vivo Gene Editing to Treat a Rare Genetic Disease.

The New England journal of medicine

Musunuru K, Grandinette SA, Wang X, Hudson TR, Briseno K, Berry AM, Hacker JL, Hsu A, Silverstein RA, Hille LT, Ogul AN, Robinson-Garvin NA, Small JC, McCague S, Burke SM, Wright CM, Bick S, Indurthi V, Sharma S, Jepperson M, Vakulskas CA, Collingwood M, Keogh K, Jacobi A, Sturgeon M, Brommel C, Schmaljohn E, Kurgan G, Osborne T, Zhang H, Kinney K, Rettig G, Barbosa CJ, Semple SC, Tam YK, Lutz C, George LA, Kleinstiver BP, Liu DR, Ng K, Kassim SH, Giannikopoulos P, Alameh MG, Urnov FD, Ahrens-Nicklas RC

A Primer on Gene Editing: What Does It Mean for Pathologists?

Archives of pathology & laboratory medicine

Cushman-Vokoun A, Schmidt RJ, Hiemenz MC, Fung M, Zhang BM, Bradshaw G, Gandhi M, Yao J, Yohe S, Beckman A, Grody WW, Giannikopoulos P

A Primer on Gene Editing.

Archives of pathology & laboratory medicine

Cushman-Vokoun A, Schmidt RJ, Hiemenz MC, Fung M, Zhang BM, Bradshaw G, Gandhi M, Yao J, Yohe S, Beckman A, Grody WW, Giannikopoulos P

Association of Upper Respiratory Streptococcus pneumoniae Colonization With Severe Acute Respiratory Syndrome Coronavirus 2 Infection Among Adults.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Parker AM, Jackson N, Awasthi S, Kim H, Alwan T, Wyllie AL, Baldwin AB, Brennick NB, Moehle EA, Giannikopoulos P, Kogut K, Holland N, Mora-Wyrobek A, Eskenazi B, Riley LW, Lewnard JA

Association of upper respiratory Streptococcus pneumoniae colonization with SARS-CoV-2 infection among adults.

medRxiv : the preprint server for health sciences

Parker AM, Jackson N, Awasthi S, Kim H, Alwan T, Wyllie AL, Baldwin AB, Brennick NB, Moehle EA, Giannikopoulos P, Kogut K, Holland N, Mora-Wyrobek A, Eskenazi B, Riley LW, Lewnard JA

Pediatric Sarcomas: The Next Generation of Molecular Studies.

Cancers

Giannikopoulos P, Parham DM

LuNER: Multiplexed SARS-CoV-2 detection in clinical swab and wastewater samples.

PloS one

Stahl EC, Gopez AR, Tsuchida CA, Fan VB, Moehle EA, Witkowsky LB, Hamilton JR, Lin-Shiao E, McElroy M, McDevitt SL, Ciling A, Tsui CK, Pestal K, Gildea HK, Keller A, Sylvain IA, Williams C, Hirsh A, Ehrenberg AJ, Kantor R, Metzger M, Nelson KL, Urnov FD, Ringeisen BR, Giannikopoulos P, Doudna JA, IGI Testing Consortium

Robotic RNA extraction for SARS-CoV-2 surveillance using saliva samples.

PloS one

Hamilton JR, Stahl EC, Tsuchida CA, Lin-Shiao E, Tsui CK, Pestal K, Gildea HK, Witkowsky LB, Moehle EA, McDevitt SL, McElroy M, Keller A, Sylvain I, Hirsh A, Ciling A, Ehrenberg AJ, Ringeisen BR, Huberty G, Urnov FD, Giannikopoulos P, Doudna JA, IGI SARS-CoV-2 Consortium

Rhabdomyosarcoma: How Advanced Molecular Methods Are Shaping the Diagnostic and Therapeutic Paradigm.

Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society

Giannikopoulos P, Parham DM

Launching a saliva-based SARS-CoV-2 surveillance testing program on a university campus.

PloS one

Ehrenberg AJ, Moehle EA, Brook CE, Doudna Cate AH, Witkowsky LB, Sachdeva R, Hirsh A, Barry K, Hamilton JR, Lin-Shiao E, McDevitt S, Valentin-Alvarado L, Letourneau KN, Hunter L, Keller A, Pestal K, Frankino PA, Murley A, Nandakumar D, Stahl EC, Tsuchida CA, Gildea HK, Murdock AG, Hochstrasser ML, O'Brien E, Ciling A, Tsitsiklis A, Worden K, Dugast-Darzacq C, Hays SG, Barber CC, McGarrigle R, Lam EK, Ensminger DC, Bardet L, Sherry C, Harte A, Nicolette G, Giannikopoulos P, Hockemeyer D, Petersen M, Urnov FD, Ringeisen BR, Boots M, Doudna JA, IGI SARS-CoV-2 Testing Consortium

Robotic RNA extraction for SARS-CoV-2 surveillance using saliva samples.

medRxiv : the preprint server for health sciences

Hamilton JR, Stahl EC, Tsuchida CA, Lin-Shiao E, Tsui CK, Pestal K, Gildea HK, Witkowsky LB, Moehle EA, McDevitt SL, McElroy M, Keller A, Sylvain I, Hirsh A, Ciling A, Ehrenberg AJ, IGI SARS-CoV-2 consortium, Ringeisen BR, Huberty G, Urnov FD, Giannikopoulos P, Doudna JA

Rhabdomyosarcoma: From Obscurity to Clarity in Diagnosis … But With Ongoing Challenges in Management: The Farber-Landing Lecture of 2020.

Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society

Parham DM, Giannikopoulos P

IGI-LuNER: single-well multiplexed RT-qPCR test for SARS-CoV-2.

medRxiv : the preprint server for health sciences

Stahl EC, Tsuchida CA, Hamilton JR, Lin-Shiao E, McDevitt SL, Moehle EA, Witkowsky LB, Tsui CK, Pestal K, Gildea HK, McElroy M, Keller A, Sylvain I, Williams C, Hirsh A, Ciling A, Ehrenberg AJ, IGI SARS-CoV-2 consortium, Urnov FD, Ringeisen BR, Giannikopoulos P, Doudna JA

Evolution and clinical impact of co-occurring genetic alterations in advanced-stage EGFR-mutant lung cancers.

Nature genetics

Blakely CM, Watkins TBK, Wu W, Gini B, Chabon JJ, McCoach CE, McGranahan N, Wilson GA, Birkbak NJ, Olivas VR, Rotow J, Maynard A, Wang V, Gubens MA, Banks KC, Lanman RB, Caulin AF, St John J, Cordero AR, Giannikopoulos P, Simmons AD, Mack PC, Gandara DR, Husain H, Doebele RC, Riess JW, Diehn M, Swanton C, Bivona TG

Oncogenic activation of the PI3-kinase p110β isoform via the tumor-derived PIK3Cβ(D1067V) kinase domain mutation.

Oncogene

Pazarentzos E, Giannikopoulos P, Hrustanovic G, St John J, Olivas VR, Gubens MA, Balassanian R, Weissman J, Polkinghorn W, Bivona TG

Exome sequencing of pleuropulmonary blastoma reveals frequent biallelic loss of TP53 and two hits in DICER1 resulting in retention of 5p-derived miRNA hairpin loop sequences.

Oncogene

Pugh TJ, Yu W, Yang J, Field AL, Ambrogio L, Carter SL, Cibulskis K, Giannikopoulos P, Kiezun A, Kim J, McKenna A, Nickerson E, Getz G, Hoffher S, Messinger YH, Dehner LP, Roberts CW, Rodriguez-Galindo C, Williams GM, Rossi CT, Meyerson M, Hill DA

The impact of EGFR T790M mutations and BIM mRNA expression on outcome in patients with EGFR-mutant NSCLC treated with erlotinib or chemotherapy in the randomized phase III EURTAC trial.

Clinical cancer research : an official journal of the American Association for Cancer Research

Costa C, Molina MA, Drozdowskyj A, Giménez-Capitán A, Bertran-Alamillo J, Karachaliou N, Gervais R, Massuti B, Wei J, Moran T, Majem M, Felip E, Carcereny E, Garcia-Campelo R, Viteri S, Taron M, Ono M, Giannikopoulos P, Bivona T, Rosell R

A retroesophageal right subclavian artery originating from the left aortic arch -- a case report and review of the literature.

Folia morphologica

Loukas M, Giannikopoulos P, Fudalej M, Dimopoulos C, Wagner T

Binding to cisplatin-modified DNA by the Saccharomyces cerevisiae HMGB protein Nhp6A.

Biochemistry

Wong B, Masse JE, Yen YM, Giannikopoulos P, Feigon J, Johnson RC, Giannikoupolous P

Petros Giannikopoulos, MD

Patient-Specific In Vivo Gene Editing to Treat a Rare Genetic Disease.

A Primer on Gene Editing: What Does It Mean for Pathologists?

A Primer on Gene Editing.

Association of Upper Respiratory Streptococcus pneumoniae Colonization With Severe Acute Respiratory Syndrome Coronavirus 2 Infection Among Adults.

Association of upper respiratory Streptococcus pneumoniae colonization with SARS-CoV-2 infection among adults.

Pediatric Sarcomas: The Next Generation of Molecular Studies.

LuNER: Multiplexed SARS-CoV-2 detection in clinical swab and wastewater samples.

Robotic RNA extraction for SARS-CoV-2 surveillance using saliva samples.

Rhabdomyosarcoma: How Advanced Molecular Methods Are Shaping the Diagnostic and Therapeutic Paradigm.

Launching a saliva-based SARS-CoV-2 surveillance testing program on a university campus.

Robotic RNA extraction for SARS-CoV-2 surveillance using saliva samples.

Rhabdomyosarcoma: From Obscurity to Clarity in Diagnosis … But With Ongoing Challenges in Management: The Farber-Landing Lecture of 2020.

IGI-LuNER: single-well multiplexed RT-qPCR test for SARS-CoV-2.

Evolution and clinical impact of co-occurring genetic alterations in advanced-stage EGFR-mutant lung cancers.

Oncogenic activation of the PI3-kinase p110β isoform via the tumor-derived PIK3Cβ(D1067V) kinase domain mutation.

Exome sequencing of pleuropulmonary blastoma reveals frequent biallelic loss of TP53 and two hits in DICER1 resulting in retention of 5p-derived miRNA hairpin loop sequences.

The impact of EGFR T790M mutations and BIM mRNA expression on outcome in patients with EGFR-mutant NSCLC treated with erlotinib or chemotherapy in the randomized phase III EURTAC trial.

The transcription factor cyclic AMP-responsive element-binding protein H regulates triglyceride metabolism.

Prenatal diagnosis of primary pulmonary hypoplasia in fraternal twins.

A case report of Noonan's syndrome with pulmonary valvar stenosis and coronary aneurysms.

A retroesophageal right subclavian artery originating from the left aortic arch -- a case report and review of the literature.

Binding to cisplatin-modified DNA by the Saccharomyces cerevisiae HMGB protein Nhp6A.

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Petros Giannikopoulos, MD